Selective vulnerability of different types of commissural neurons for amyloid  -protein-induced neurodegeneration in APP23 mice correlates with dendritic tree morphology

The amyloid β-protein (Aβ) is the main component of Alzheimer's disease-related senile plaques. Although Aβ is associated with the development of Alzheimer's disease, it has not been shown which forms of Aβ induce neurodegeneration in vivo and which types of neurons are vulnerable. To addr...

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Veröffentlicht in:Brain (London, England : 1878) England : 1878), 2006-11, Vol.129 (11), p.2992-3005
Hauptverfasser: Capetillo-Zarate, Estibaliz, Staufenbiel, Matthias, Abramowski, Dorothee, Haass, Christian, Escher, Angelika, Stadelmann, Christine, Yamaguchi, Haruyasu, Wiestler, Otmar D, Thal, Dietmar Rudolf
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Sprache:eng
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