Epigenetic Histone Modifications Do Not Control Igκ Locus Contraction and Intranuclear Localization in Cells with Dual B Cell-Macrophage Potential

Somatic rearrangement of the Ig genes during B cell development is believed to be controlled, at least in part, by accessibility of the loci to the recombinational machinery. Accessibility is poorly understood, but appears to be controlled by a combination of histone posttranslational modifications,...

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Veröffentlicht in:Journal of Immunology 2006-11, Vol.177 (9), p.6165-6171
Hauptverfasser: Hodawadekar, Suchita, Wei, Fang, Yu, Duonan, Thomas-Tikhonenko, Andrei, Atchison, Michael L.
Format: Artikel
Sprache:eng
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