Graphene-based nanomaterials for drug and/or gene delivery, bioimaging, and tissue engineering
•Graphene-based nanomaterials are emerging as the next generation’s candidates for biotechnological advancements.•Graphene and its various derivatives have been covered.•The properties of graphene-based materials related to biomedical applications have been discussed.•The review emphasizes the up-to...
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| Veröffentlicht in: | Drug discovery today 2017-09, Vol.22 (9), p.1302-1317 |
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| container_end_page | 1317 |
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| container_issue | 9 |
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| container_title | Drug discovery today |
| container_volume | 22 |
| creator | Zhao, Hong Ding, Ruihua Zhao, Xin Li, Yiwei Qu, Liangliang Pei, Hao Yildirimer, Lara Wu, Zhengwei Zhang, Weixia |
| description | •Graphene-based nanomaterials are emerging as the next generation’s candidates for biotechnological advancements.•Graphene and its various derivatives have been covered.•The properties of graphene-based materials related to biomedical applications have been discussed.•The review emphasizes the up-to-date biomedical applications of graphene-based materials.•It also covers the rising concern about the toxicity of graphene-based materials.
Here, we discuss the biomedical applications of graphene-based nanomaterials (GBNs). We examine graphene and its various derivatives, including graphene, graphene oxides (GOs), reduced graphene oxides (rGOs), graphene quantum dots (GQDs), and graphene composites, and discuss their unique properties related to their biomedical applications. We also summarize the detailed biomedical applications of GBNs, including drug and/or gene delivery, bioimaging, and tissue engineering. We also highlight the toxicity of these nanomaterials. |
| doi_str_mv | 10.1016/j.drudis.2017.04.002 |
| format | Article |
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Here, we discuss the biomedical applications of graphene-based nanomaterials (GBNs). We examine graphene and its various derivatives, including graphene, graphene oxides (GOs), reduced graphene oxides (rGOs), graphene quantum dots (GQDs), and graphene composites, and discuss their unique properties related to their biomedical applications. We also summarize the detailed biomedical applications of GBNs, including drug and/or gene delivery, bioimaging, and tissue engineering. We also highlight the toxicity of these nanomaterials.</description><identifier>ISSN: 1359-6446</identifier><identifier>EISSN: 1878-5832</identifier><identifier>DOI: 10.1016/j.drudis.2017.04.002</identifier><identifier>PMID: 28869820</identifier><language>eng</language><publisher>England: Elsevier Ltd</publisher><subject>Animals ; Diagnostic Imaging ; Drug Delivery Systems ; Gene Transfer Techniques ; Graphite - administration & dosage ; Graphite - chemistry ; Humans ; Nanostructures - administration & dosage ; Nanostructures - chemistry ; Tissue Engineering</subject><ispartof>Drug discovery today, 2017-09, Vol.22 (9), p.1302-1317</ispartof><rights>2017 Elsevier Ltd</rights><rights>Copyright © 2017 Elsevier Ltd. All rights reserved.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c474t-d81f28b424ec3d35e80ac5b39de8656c9333b32447ed8fa314c94337b415fc263</citedby><cites>FETCH-LOGICAL-c474t-d81f28b424ec3d35e80ac5b39de8656c9333b32447ed8fa314c94337b415fc263</cites><orcidid>0000-0002-5835-2020</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.drudis.2017.04.002$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>315,781,785,3551,27929,27930,46000</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28869820$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Zhao, Hong</creatorcontrib><creatorcontrib>Ding, Ruihua</creatorcontrib><creatorcontrib>Zhao, Xin</creatorcontrib><creatorcontrib>Li, Yiwei</creatorcontrib><creatorcontrib>Qu, Liangliang</creatorcontrib><creatorcontrib>Pei, Hao</creatorcontrib><creatorcontrib>Yildirimer, Lara</creatorcontrib><creatorcontrib>Wu, Zhengwei</creatorcontrib><creatorcontrib>Zhang, Weixia</creatorcontrib><title>Graphene-based nanomaterials for drug and/or gene delivery, bioimaging, and tissue engineering</title><title>Drug discovery today</title><addtitle>Drug Discov Today</addtitle><description>•Graphene-based nanomaterials are emerging as the next generation’s candidates for biotechnological advancements.•Graphene and its various derivatives have been covered.•The properties of graphene-based materials related to biomedical applications have been discussed.•The review emphasizes the up-to-date biomedical applications of graphene-based materials.•It also covers the rising concern about the toxicity of graphene-based materials.
Here, we discuss the biomedical applications of graphene-based nanomaterials (GBNs). We examine graphene and its various derivatives, including graphene, graphene oxides (GOs), reduced graphene oxides (rGOs), graphene quantum dots (GQDs), and graphene composites, and discuss their unique properties related to their biomedical applications. We also summarize the detailed biomedical applications of GBNs, including drug and/or gene delivery, bioimaging, and tissue engineering. We also highlight the toxicity of these nanomaterials.</description><subject>Animals</subject><subject>Diagnostic Imaging</subject><subject>Drug Delivery Systems</subject><subject>Gene Transfer Techniques</subject><subject>Graphite - administration & dosage</subject><subject>Graphite - chemistry</subject><subject>Humans</subject><subject>Nanostructures - administration & dosage</subject><subject>Nanostructures - chemistry</subject><subject>Tissue Engineering</subject><issn>1359-6446</issn><issn>1878-5832</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kF1LwzAUhoMobk7_gUgvvbBdPtv0RpChUxC80VtDmpzWjC2dSTvw35sx9dKrHMJz3pfzIHRJcEEwKeerwobRulhQTKoC8wJjeoSmRFYyF5LR4zQzUecl5-UEncW4wpjQWpSnaEKlLGtJ8RS9L4PefoCHvNERbOa17zd6gOD0OmZtH7LU0mXa23mauwRmFtZuB-HrJmtc7za6c7672RPZ4GIcIQOfviBF-O4cnbQpCC5-3hl6e7h_XTzmzy_Lp8Xdc254xYfcStJS2XDKwTDLBEisjWhYbUGWojQ1Y6xhlPMKrGw1I9zUnLGq4US0hpZshq4PudvQf44QB7Vx0cB6rT30Y1SkZkISUgmSUH5ATehjDNCqbUhXhC9FsNqbVSt1MKv2ZhXmKplNa1c_DWOzAfu39KsyAbcHANKdOwdBRePAG7AugBmU7d3_Dd_d34w7</recordid><startdate>201709</startdate><enddate>201709</enddate><creator>Zhao, Hong</creator><creator>Ding, Ruihua</creator><creator>Zhao, Xin</creator><creator>Li, Yiwei</creator><creator>Qu, Liangliang</creator><creator>Pei, Hao</creator><creator>Yildirimer, Lara</creator><creator>Wu, Zhengwei</creator><creator>Zhang, Weixia</creator><general>Elsevier Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-5835-2020</orcidid></search><sort><creationdate>201709</creationdate><title>Graphene-based nanomaterials for drug and/or gene delivery, bioimaging, and tissue engineering</title><author>Zhao, Hong ; Ding, Ruihua ; Zhao, Xin ; Li, Yiwei ; Qu, Liangliang ; Pei, Hao ; Yildirimer, Lara ; Wu, Zhengwei ; Zhang, Weixia</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c474t-d81f28b424ec3d35e80ac5b39de8656c9333b32447ed8fa314c94337b415fc263</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Animals</topic><topic>Diagnostic Imaging</topic><topic>Drug Delivery Systems</topic><topic>Gene Transfer Techniques</topic><topic>Graphite - administration & dosage</topic><topic>Graphite - chemistry</topic><topic>Humans</topic><topic>Nanostructures - administration & dosage</topic><topic>Nanostructures - chemistry</topic><topic>Tissue Engineering</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Zhao, Hong</creatorcontrib><creatorcontrib>Ding, Ruihua</creatorcontrib><creatorcontrib>Zhao, Xin</creatorcontrib><creatorcontrib>Li, Yiwei</creatorcontrib><creatorcontrib>Qu, Liangliang</creatorcontrib><creatorcontrib>Pei, Hao</creatorcontrib><creatorcontrib>Yildirimer, Lara</creatorcontrib><creatorcontrib>Wu, Zhengwei</creatorcontrib><creatorcontrib>Zhang, Weixia</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Drug discovery today</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Zhao, Hong</au><au>Ding, Ruihua</au><au>Zhao, Xin</au><au>Li, Yiwei</au><au>Qu, Liangliang</au><au>Pei, Hao</au><au>Yildirimer, Lara</au><au>Wu, Zhengwei</au><au>Zhang, Weixia</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Graphene-based nanomaterials for drug and/or gene delivery, bioimaging, and tissue engineering</atitle><jtitle>Drug discovery today</jtitle><addtitle>Drug Discov Today</addtitle><date>2017-09</date><risdate>2017</risdate><volume>22</volume><issue>9</issue><spage>1302</spage><epage>1317</epage><pages>1302-1317</pages><issn>1359-6446</issn><eissn>1878-5832</eissn><abstract>•Graphene-based nanomaterials are emerging as the next generation’s candidates for biotechnological advancements.•Graphene and its various derivatives have been covered.•The properties of graphene-based materials related to biomedical applications have been discussed.•The review emphasizes the up-to-date biomedical applications of graphene-based materials.•It also covers the rising concern about the toxicity of graphene-based materials.
Here, we discuss the biomedical applications of graphene-based nanomaterials (GBNs). We examine graphene and its various derivatives, including graphene, graphene oxides (GOs), reduced graphene oxides (rGOs), graphene quantum dots (GQDs), and graphene composites, and discuss their unique properties related to their biomedical applications. We also summarize the detailed biomedical applications of GBNs, including drug and/or gene delivery, bioimaging, and tissue engineering. We also highlight the toxicity of these nanomaterials.</abstract><cop>England</cop><pub>Elsevier Ltd</pub><pmid>28869820</pmid><doi>10.1016/j.drudis.2017.04.002</doi><tpages>16</tpages><orcidid>https://orcid.org/0000-0002-5835-2020</orcidid><oa>free_for_read</oa></addata></record> |
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| source | MEDLINE; Access via ScienceDirect (Elsevier) |
| subjects | Animals Diagnostic Imaging Drug Delivery Systems Gene Transfer Techniques Graphite - administration & dosage Graphite - chemistry Humans Nanostructures - administration & dosage Nanostructures - chemistry Tissue Engineering |
| title | Graphene-based nanomaterials for drug and/or gene delivery, bioimaging, and tissue engineering |
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