Structural studies and nociceptive activity of a native lectin from Platypodium elegans seeds (nPELa)

•We present the three-dimensional structure of Platypodium elegans Hook seed lectin (PELa).•Molecular docking and dynamics analysis of PELa structure was performed.•We evaluated the nociceptive effect of PELa in rats. A native lectin (nPELa), purified from seeds of the species Platypodium elegans, D...

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Veröffentlicht in:International journal of biological macromolecules 2018-02, Vol.107 (Pt A), p.236-246
Hauptverfasser: Cavada, Benildo Sousa, Araripe, David Alencar, Silva, Ivanice Bezerra, Pinto-Junior, Vanir Reis, Osterne, Vinicius Jose Silva, Neco, Antonio Hadson Bastos, Laranjeira, Eva Pollyanna Peixe, Lossio, Claudia Figueiredo, Correia, Jorge Luis Almeida, Pires, Alana Freitas, Assreuy, Ana Maria Sampaio, Nascimento, Kyria Santiago
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Sprache:eng
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