Anti-hyperlipidemic effect of rice bran polysaccharide and its potential mechanism in high-fat diet mice

Hyperlipidemia occurs very often in modern society along with a high calorie intake and is regarded as one of the greatest risk factors for the prevalence of cardiac vascular disease (CVD). In this study, we investigated the anti-hyperlipidemic effect of the rice bran polysaccharides (RBP) and its m...

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Veröffentlicht in:	Food & function 2017-11, Vol.8 (11), p.428-441
Hauptverfasser:	Nie, Ying, Luo, Feijun, Wang, Long, Yang, Tao, Shi, Limin, Li, Xinhua, Shen, Junjun, Xu, Wei, Guo, Ting, Lin, Qinlu
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipose tissue Animal tissues Animals Body weight CD36 antigen Cholesterol Cholesterol - metabolism Coronary artery disease Diet Diet, High-Fat - adverse effects Dietary supplements DNA microarrays Gene expression Genes Heart diseases High fat diet Humans Hyperlipidemia Hyperlipidemias - drug therapy Hyperlipidemias - genetics Hyperlipidemias - metabolism Hypolipidemic Agents - administration & dosage Lipid metabolism Lipids Lipoproteins, LDL - metabolism Liver Low density lipoprotein Male Metabolism Mice Mice, Inbred C57BL Mice, Inbred ICR NF-κB protein Oral administration Oryza - chemistry Peroxisome proliferator-activated receptors Plant Extracts - administration & dosage Polysaccharides Polysaccharides - administration & dosage PPAR alpha - genetics PPAR alpha - metabolism Rice bran Risk analysis Risk factors Rodents Saccharides Sterol Regulatory Element Binding Protein 1 - genetics Sterol Regulatory Element Binding Protein 1 - metabolism Sterol regulatory element-binding protein Triglycerides Triglycerides - metabolism Vascular diseases Water treatment
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