AMPK attenuates ventricular remodeling and dysfunction following aortic banding in mice via the Sirt3/Oxidative stress pathway

Although recent findings have suggested that AMP-activated protein kinase (AMPK) exerts inhibitory effects on cardiac remodeling secondary to hypertension, the mechanism and optimal duration of treatment remain unknown. Mice with descending aortic banding (AB) or subjected to sham operation received...

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Veröffentlicht in:European journal of pharmacology 2017-11, Vol.814, p.335-342
Hauptverfasser: Chen, Yili, Chen, Cong, Dong, Bin, Xing, Fuwei, Huang, Huiling, Yao, Fengjuan, Ma, Yuedong, He, Jiangui, Dong, Yugang
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Sprache:eng
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