Stem cell transplantation for Huntington’s diseases

•Huntington’s disease (HD) is caused by loss of GABAergic MSNs in the striatum.•The MSNs grafted with NSCs must send out their axons and receive the correct input.•NSCs with low risks of teratoma formation could be suitable source for HD treatment.•NSCs obtained from HD patients must be genetically...

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Veröffentlicht in:	Methods (San Diego, Calif.) Calif.), 2018-01, Vol.133, p.104-112
Hauptverfasser:	Choi, Kyung-Ah, Choi, Yeonho, Hong, Sunghoi
Format:	Artikel
Sprache:	eng
Schlagworte:	Gene correction Huntington’s disease Induced neural stem cells Stem cell-based therapies Transplantation
Online-Zugang:	Volltext
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