Inhibition of BMP signaling during zebrafish fin regeneration disrupts fin growth and scleroblast differentiation and function

The zebrafish caudal fin provides a simple model to study molecular mechanisms of dermal bone regeneration. We previously showed that misexpression of Bone morphogenetic protein 2b (Bmp2b) induces ectopic bone formation within the regenerate. Here we show that in addition to bmp2b and bmp4 another f...

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Veröffentlicht in:	Developmental biology 2006-11, Vol.299 (2), p.438-454
Hauptverfasser:	Smith, A., Avaron, F., Guay, D., Padhi, B.K., Akimenko, M.A.
Format:	Artikel
Sprache:	eng
Schlagworte:	BMP signaling Chordin Col10a1 Col2a1 Danio rerio Fin regeneration Freshwater Intramembranous bone Runx2 Sox9 Zebrafish
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