A comparison of the cost–utility of ultrasound‐guided high‐intensity focused ultrasound and hysterectomy for adenomyosis: a retrospective study

Objective To evaluate cost‐effectiveness of ultrasound‐guided high‐intensity focused ultrasound (USgHIFU) and open hysterectomy for adenomyosis. Design A retrospective analysis. Setting Gynaecological department in a single centre in China. Population Patients with symptomatic adenomyosis. Main outc...

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Veröffentlicht in:BJOG : an international journal of obstetrics and gynaecology 2017-08, Vol.124 (S3), p.40-45
Hauptverfasser: Liu, XF, Huang, LH, Zhang, C, Huang, GH, Yan, LM, He, J
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container_issue S3
container_start_page 40
container_title BJOG : an international journal of obstetrics and gynaecology
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creator Liu, XF
Huang, LH
Zhang, C
Huang, GH
Yan, LM
He, J
description Objective To evaluate cost‐effectiveness of ultrasound‐guided high‐intensity focused ultrasound (USgHIFU) and open hysterectomy for adenomyosis. Design A retrospective analysis. Setting Gynaecological department in a single centre in China. Population Patients with symptomatic adenomyosis. Main outcome measures Cost difference between patients with adenomyosis treated with USgHIFU and open hysterectomy. Methods Three hundred and sixty‐eight patients with adenomyosis were retrospectively reviewed. Among them, 302 patients were treated with USgHIFU and 66 patients with open hysterectomy. All of them had 1‐, 3‐, 6‐ and 12‐month follow ups. The patients’ quality of life (QOL) was evaluated and the utility scores were obtained from a rating scale to conduct a cost–utility analysis (CUA). Results No significant differences were found at any follow‐up time point in the QOL between the two groups (P > 0.05). After treatment, the QOL scores significantly increased in both groups (P 
doi_str_mv 10.1111/1471-0528.14746
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Design A retrospective analysis. Setting Gynaecological department in a single centre in China. Population Patients with symptomatic adenomyosis. Main outcome measures Cost difference between patients with adenomyosis treated with USgHIFU and open hysterectomy. Methods Three hundred and sixty‐eight patients with adenomyosis were retrospectively reviewed. Among them, 302 patients were treated with USgHIFU and 66 patients with open hysterectomy. All of them had 1‐, 3‐, 6‐ and 12‐month follow ups. The patients’ quality of life (QOL) was evaluated and the utility scores were obtained from a rating scale to conduct a cost–utility analysis (CUA). Results No significant differences were found at any follow‐up time point in the QOL between the two groups (P &gt; 0.05). After treatment, the QOL scores significantly increased in both groups (P &lt; 0.05): the quality adjusted life year (QALY) for patients treated with USgHIFU was USUS$5256.48, whereas it was USUS$7510.03 for patients treated with open hysterectomy. Both incremental cost and sensitivity analysis showed that USgHIFU was less costly than open hysterectomy. Conclusions The QOL of patients with adenomyosis can be significantly improved by either USgHIFU or open hysterectomy, but USgHIFU is less costly. Tweetable USgHIFU can safely be used to treat patients with adenomyosis and significantly improved the quality of life of patients after treatment. The cost of USgHIFU is less than that of surgical treatment. Tweetable USg HIFU can safely be used to treat patients with adenomyosis and significantly improved the quality of life of patients after treatment. The cost of USgHIFU is less than that of surgical treatment.</description><identifier>ISSN: 1470-0328</identifier><identifier>EISSN: 1471-0528</identifier><identifier>DOI: 10.1111/1471-0528.14746</identifier><identifier>PMID: 28856866</identifier><language>eng</language><publisher>England: Wiley Subscription Services, Inc</publisher><subject>Adenomyosis ; Adenomyosis - economics ; Adenomyosis - psychology ; Adenomyosis - surgery ; Adult ; Comparative studies ; Cost analysis ; Cost-Benefit Analysis ; cost–utility analysis ; Female ; Gynecology ; Health care expenditures ; High-Intensity Focused Ultrasound Ablation - economics ; High-Intensity Focused Ultrasound Ablation - methods ; High-Intensity Focused Ultrasound Ablation - psychology ; high‐intensity focused ultrasound ; Humans ; Hysterectomy ; Hysterectomy - economics ; Hysterectomy - methods ; Hysterectomy - psychology ; Middle Aged ; open hysterectomy ; Preoperative Care - methods ; Quality of Life ; Quality-Adjusted Life Years ; Reproductive system ; Retrospective Studies ; Sensitivity analysis ; Treatment Outcome ; Ultrasonic technology ; Ultrasound</subject><ispartof>BJOG : an international journal of obstetrics and gynaecology, 2017-08, Vol.124 (S3), p.40-45</ispartof><rights>2017 Royal College of Obstetricians and Gynaecologists</rights><rights>2017 Royal College of Obstetricians and Gynaecologists.</rights><rights>Copyright © 2017 Royal College of Obstetricians and Gynaecologists</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4126-27557e537c3eea30b3d39683f3e327ebbe49032ddd8ebeac6fb73811f0b668143</citedby><cites>FETCH-LOGICAL-c4126-27557e537c3eea30b3d39683f3e327ebbe49032ddd8ebeac6fb73811f0b668143</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2F1471-0528.14746$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2F1471-0528.14746$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27901,27902,45550,45551</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28856866$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Liu, XF</creatorcontrib><creatorcontrib>Huang, LH</creatorcontrib><creatorcontrib>Zhang, C</creatorcontrib><creatorcontrib>Huang, GH</creatorcontrib><creatorcontrib>Yan, LM</creatorcontrib><creatorcontrib>He, J</creatorcontrib><title>A comparison of the cost–utility of ultrasound‐guided high‐intensity focused ultrasound and hysterectomy for adenomyosis: a retrospective study</title><title>BJOG : an international journal of obstetrics and gynaecology</title><addtitle>BJOG</addtitle><description>Objective To evaluate cost‐effectiveness of ultrasound‐guided high‐intensity focused ultrasound (USgHIFU) and open hysterectomy for adenomyosis. Design A retrospective analysis. Setting Gynaecological department in a single centre in China. Population Patients with symptomatic adenomyosis. Main outcome measures Cost difference between patients with adenomyosis treated with USgHIFU and open hysterectomy. Methods Three hundred and sixty‐eight patients with adenomyosis were retrospectively reviewed. Among them, 302 patients were treated with USgHIFU and 66 patients with open hysterectomy. All of them had 1‐, 3‐, 6‐ and 12‐month follow ups. The patients’ quality of life (QOL) was evaluated and the utility scores were obtained from a rating scale to conduct a cost–utility analysis (CUA). Results No significant differences were found at any follow‐up time point in the QOL between the two groups (P &gt; 0.05). After treatment, the QOL scores significantly increased in both groups (P &lt; 0.05): the quality adjusted life year (QALY) for patients treated with USgHIFU was USUS$5256.48, whereas it was USUS$7510.03 for patients treated with open hysterectomy. Both incremental cost and sensitivity analysis showed that USgHIFU was less costly than open hysterectomy. Conclusions The QOL of patients with adenomyosis can be significantly improved by either USgHIFU or open hysterectomy, but USgHIFU is less costly. Tweetable USgHIFU can safely be used to treat patients with adenomyosis and significantly improved the quality of life of patients after treatment. The cost of USgHIFU is less than that of surgical treatment. Tweetable USg HIFU can safely be used to treat patients with adenomyosis and significantly improved the quality of life of patients after treatment. The cost of USgHIFU is less than that of surgical treatment.</description><subject>Adenomyosis</subject><subject>Adenomyosis - economics</subject><subject>Adenomyosis - psychology</subject><subject>Adenomyosis - surgery</subject><subject>Adult</subject><subject>Comparative studies</subject><subject>Cost analysis</subject><subject>Cost-Benefit Analysis</subject><subject>cost–utility analysis</subject><subject>Female</subject><subject>Gynecology</subject><subject>Health care expenditures</subject><subject>High-Intensity Focused Ultrasound Ablation - economics</subject><subject>High-Intensity Focused Ultrasound Ablation - methods</subject><subject>High-Intensity Focused Ultrasound Ablation - psychology</subject><subject>high‐intensity focused ultrasound</subject><subject>Humans</subject><subject>Hysterectomy</subject><subject>Hysterectomy - economics</subject><subject>Hysterectomy - methods</subject><subject>Hysterectomy - psychology</subject><subject>Middle Aged</subject><subject>open hysterectomy</subject><subject>Preoperative Care - methods</subject><subject>Quality of Life</subject><subject>Quality-Adjusted Life Years</subject><subject>Reproductive system</subject><subject>Retrospective Studies</subject><subject>Sensitivity analysis</subject><subject>Treatment Outcome</subject><subject>Ultrasonic technology</subject><subject>Ultrasound</subject><issn>1470-0328</issn><issn>1471-0528</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkc1O3TAQha2qVaG0a3bIUjfdBOw4cXzZUdRfIbGBteXEE65REl88dqvseIRKiBfkSepwKZW6qSXL4-Nvjjw6hOxzdsjzOuJVwwtWl-owV5V8QXaflZePNSuYKNUOeYN4zRiXJROvyU6pVC2VlLvk_oR2ftyY4NBP1Pc0riErGB9u71J0g4vzoqYhBoM-Tfbh9tdVchYsXburdb65KcKEC9f7LmF--AtTk_d6xggBuujHhQnUWJhy7dHhMTU0QAweNxlwP4BiTHZ-S171ZkB493TukcvPny5OvxZn51--nZ6cFV3FS1mUTV03UIumEwBGsFZYsZJK9AJE2UDbQrXK41trFbRgOtm3jVCc96yVUvFK7JEPW99N8DcJMOrRYQfDYCbwCTVfiapUrKpFRt__g177FKb8u4USql41jGfqaEt1eSQM0OtNcKMJs-ZML4npJR-95KMfE8sdB0--qR3BPvN_IspAvQV-ugHm__npj9_Pt8a_AR1Ppn4</recordid><startdate>201708</startdate><enddate>201708</enddate><creator>Liu, XF</creator><creator>Huang, LH</creator><creator>Zhang, C</creator><creator>Huang, GH</creator><creator>Yan, LM</creator><creator>He, J</creator><general>Wiley Subscription Services, Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QP</scope><scope>ASE</scope><scope>FPQ</scope><scope>K6X</scope><scope>K9.</scope><scope>7X8</scope></search><sort><creationdate>201708</creationdate><title>A comparison of the cost–utility of ultrasound‐guided high‐intensity focused ultrasound and hysterectomy for adenomyosis: a retrospective study</title><author>Liu, XF ; Huang, LH ; Zhang, C ; Huang, GH ; Yan, LM ; He, J</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4126-27557e537c3eea30b3d39683f3e327ebbe49032ddd8ebeac6fb73811f0b668143</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Adenomyosis</topic><topic>Adenomyosis - economics</topic><topic>Adenomyosis - psychology</topic><topic>Adenomyosis - surgery</topic><topic>Adult</topic><topic>Comparative studies</topic><topic>Cost analysis</topic><topic>Cost-Benefit Analysis</topic><topic>cost–utility analysis</topic><topic>Female</topic><topic>Gynecology</topic><topic>Health care expenditures</topic><topic>High-Intensity Focused Ultrasound Ablation - economics</topic><topic>High-Intensity Focused Ultrasound Ablation - methods</topic><topic>High-Intensity Focused Ultrasound Ablation - psychology</topic><topic>high‐intensity focused ultrasound</topic><topic>Humans</topic><topic>Hysterectomy</topic><topic>Hysterectomy - economics</topic><topic>Hysterectomy - methods</topic><topic>Hysterectomy - psychology</topic><topic>Middle Aged</topic><topic>open hysterectomy</topic><topic>Preoperative Care - methods</topic><topic>Quality of Life</topic><topic>Quality-Adjusted Life Years</topic><topic>Reproductive system</topic><topic>Retrospective Studies</topic><topic>Sensitivity analysis</topic><topic>Treatment Outcome</topic><topic>Ultrasonic technology</topic><topic>Ultrasound</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Liu, XF</creatorcontrib><creatorcontrib>Huang, LH</creatorcontrib><creatorcontrib>Zhang, C</creatorcontrib><creatorcontrib>Huang, GH</creatorcontrib><creatorcontrib>Yan, LM</creatorcontrib><creatorcontrib>He, J</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Calcium &amp; Calcified Tissue Abstracts</collection><collection>British Nursing Index</collection><collection>British Nursing Index (BNI) (1985 to Present)</collection><collection>British Nursing Index</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>MEDLINE - Academic</collection><jtitle>BJOG : an international journal of obstetrics and gynaecology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Liu, XF</au><au>Huang, LH</au><au>Zhang, C</au><au>Huang, GH</au><au>Yan, LM</au><au>He, J</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A comparison of the cost–utility of ultrasound‐guided high‐intensity focused ultrasound and hysterectomy for adenomyosis: a retrospective study</atitle><jtitle>BJOG : an international journal of obstetrics and gynaecology</jtitle><addtitle>BJOG</addtitle><date>2017-08</date><risdate>2017</risdate><volume>124</volume><issue>S3</issue><spage>40</spage><epage>45</epage><pages>40-45</pages><issn>1470-0328</issn><eissn>1471-0528</eissn><abstract>Objective To evaluate cost‐effectiveness of ultrasound‐guided high‐intensity focused ultrasound (USgHIFU) and open hysterectomy for adenomyosis. Design A retrospective analysis. Setting Gynaecological department in a single centre in China. Population Patients with symptomatic adenomyosis. Main outcome measures Cost difference between patients with adenomyosis treated with USgHIFU and open hysterectomy. Methods Three hundred and sixty‐eight patients with adenomyosis were retrospectively reviewed. Among them, 302 patients were treated with USgHIFU and 66 patients with open hysterectomy. All of them had 1‐, 3‐, 6‐ and 12‐month follow ups. The patients’ quality of life (QOL) was evaluated and the utility scores were obtained from a rating scale to conduct a cost–utility analysis (CUA). Results No significant differences were found at any follow‐up time point in the QOL between the two groups (P &gt; 0.05). After treatment, the QOL scores significantly increased in both groups (P &lt; 0.05): the quality adjusted life year (QALY) for patients treated with USgHIFU was USUS$5256.48, whereas it was USUS$7510.03 for patients treated with open hysterectomy. Both incremental cost and sensitivity analysis showed that USgHIFU was less costly than open hysterectomy. Conclusions The QOL of patients with adenomyosis can be significantly improved by either USgHIFU or open hysterectomy, but USgHIFU is less costly. Tweetable USgHIFU can safely be used to treat patients with adenomyosis and significantly improved the quality of life of patients after treatment. The cost of USgHIFU is less than that of surgical treatment. Tweetable USg HIFU can safely be used to treat patients with adenomyosis and significantly improved the quality of life of patients after treatment. The cost of USgHIFU is less than that of surgical treatment.</abstract><cop>England</cop><pub>Wiley Subscription Services, Inc</pub><pmid>28856866</pmid><doi>10.1111/1471-0528.14746</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record>
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subjects Adenomyosis
Adenomyosis - economics
Adenomyosis - psychology
Adenomyosis - surgery
Adult
Comparative studies
Cost analysis
Cost-Benefit Analysis
cost–utility analysis
Female
Gynecology
Health care expenditures
High-Intensity Focused Ultrasound Ablation - economics
High-Intensity Focused Ultrasound Ablation - methods
High-Intensity Focused Ultrasound Ablation - psychology
high‐intensity focused ultrasound
Humans
Hysterectomy
Hysterectomy - economics
Hysterectomy - methods
Hysterectomy - psychology
Middle Aged
open hysterectomy
Preoperative Care - methods
Quality of Life
Quality-Adjusted Life Years
Reproductive system
Retrospective Studies
Sensitivity analysis
Treatment Outcome
Ultrasonic technology
Ultrasound
title A comparison of the cost–utility of ultrasound‐guided high‐intensity focused ultrasound and hysterectomy for adenomyosis: a retrospective study
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