Normal 123 I-MIBG uptake areas may be associated with hyperinnervation and arrhythmia risk in phenol model rabbit hearts

Iodine-123 metaiodobenzylguanidine ( I-MIBG) is useful for detecting sympathetic innervation in the heart, and has been closely associated with fatal arrhythmias. However, such imaging is typically calibrated to the area of highest uptake and thus is unable to identify areas of hyperinnervation. We...

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Veröffentlicht in:	Pacing and clinical electrophysiology 2017-10, Vol.40 (10), p.1103-1112
Hauptverfasser:	Amino, Mari, Yoshioka, Koichiro, Tanaka, Sachie, Kawabe, Noboru, Kurosawa, Hiroyuki, Uchida, Keisuke, Oshikiri, Shinobu, Hashida, Tadashi, Kanda, Shigetaka, Inokuchi, Sadaki, Ikari, Yuji
Format:	Artikel
Sprache:	eng
Schlagworte:	3-Iodobenzylguanidine - pharmacokinetics Animals Arrhythmias, Cardiac - etiology Disease Models, Animal Heart - innervation Male Myocardium - metabolism Phenol Rabbits Radiopharmaceuticals - pharmacokinetics Risk Factors Tissue Distribution
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