Comparison of enzymically glucuronidated flavonoids with flavonoid aglycones in an in vitro cellular model of oxidative stress protection

This study modeled, in vitro, the potential effect of conjugative (phase II) metabolism on the cytoprotective capacity of fruit flavonoids against oxidative stress. Flavonoid aglycones were compared with their corresponding isomeric mixtures of glucuronides for their ability to enhance the survival...

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Veröffentlicht in:	In vitro cellular & developmental biology. Animal 2008-03, Vol.44 (3), p.73-80
Hauptverfasser:	Stevenson, David E, Cooney, Janine M, Jensen, Dwayne J, Wibisono, Reginald, Adaim, Aselle, Skinner, Margot A, Zhang, Jingli
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal Genetics and Genomics Antioxidant Antioxidants - pharmacology Biomedical and Life Sciences Cell and Tissue Models Cell Biology Cell Culture Cell death Cell Line, Tumor Cell lines Cell Survival - drug effects Cytoprotection Developmental Biology Dose response relationship Enzymes Enzymic glucuronidation Flavonoids Flavonoids - pharmacology Glucuronides Glucuronides - pharmacology Glycosides Humans Hydrogen Hydrogen Peroxide - pharmacology Life Sciences Metabolism Neurons Oxidative Stress - drug effects Polyphenol Stem Cells T lymphocytes
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