Migration of immature mouse DC across resting enhelium is mediated by ICAM-2 but independent of [bgr] sub(2)-integrins and murine DC-SIGN homologues

Immature dendritic cells (DC) reside in tissues where they initiate immune responses by taking up foreign antigens. Since DC have a limited tissue half- life, the DC pool in tissues has to be replenished constantly. This implies that precursor/immature DC must be able to cross non-activated enhelium...

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Veröffentlicht in:European Journal of Immunology 2006-01, Vol.36 (10), p.2781-2794
Hauptverfasser: Wethmar, Klaus, Helmus, Yvonne, Luehn, Kerstin, Jones, Claire, Laskowska, Anna, Varga, Georg, Grabbe, Stephan, Lyck, Ruth, Engelhardt, Britta, Bixel, MGabriele, Butz, Stefan, Loser, Karin, Beissert, Stefan, Ipe, Ute, Vestweber, Dietmar, Wild, Martin K
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Sprache:eng
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