Charting the dynamic epigenome during B-cell development

The epigenetic landscape undergoes a widespread modulation during embryonic development and cell differentiation. Within the hematopoietic system, B cells are perhaps the cell lineage with a more dynamic DNA methylome during their maturation process, which involves approximately one third of all the...

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Veröffentlicht in:	Seminars in cancer biology 2018-08, Vol.51, p.139-148
Hauptverfasser:	Martin-Subero, Jose I., Oakes, Christopher C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging Animals B cell B-Lymphocytes - metabolism B-Lymphocytes - pathology Cancer Cell Differentiation Cellular longevity DNA Methylation Epigenesis, Genetic Epigenetics Epigenomics Gene Expression Regulation, Leukemic Genome, Human Humans Transcription factors
Online-Zugang:	Volltext
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