Neutrophil migration in mice induced by a mannose-binding lectin isolated from Annona coriacea seeds

A novel 14-kDa lectin from Annona coriacea seeds (ACLEC) with hemagglutinating activity on erythrocytes has been recently described. Since plant lectins are known to present inflammatory activity, this study aimed to investigate the leukocyte migration induced by ACLEC, and inflammatory mediators in...

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Veröffentlicht in:	Toxicon (Oxford) 2006-10, Vol.48 (5), p.529-535
Hauptverfasser:	Coelho, Mirela B., DeSouza, Ivani A., Freire, Maria Graça M., Marangoni, Sérgio, Antunes, Edson, Macedo, Maria Lígia R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Annona - chemistry Annona coriacea Annona coriacea lectin Biological and medical sciences Celecoxib Chemotaxis, Leukocyte - drug effects Chemotaxis, Leukocyte - immunology Dihydropyridines - pharmacology Dose-Response Relationship, Drug Inflammation Leukocytes, Mononuclear - drug effects Leukocytes, Mononuclear - immunology Leukocytes, Mononuclear - pathology Male Mannose - pharmacology Mannose-Binding Lectin - immunology Mannose-Binding Lectin - toxicity Medical sciences Mice Neutrophil migration Neutrophils - drug effects Neutrophils - immunology Neutrophils - pathology Peritoneal Cavity Plant Extracts - immunology Plant Extracts - toxicity Plant poisons toxicology Pyrazoles - pharmacology Seeds - chemistry Sulfonamides - pharmacology Toxicology
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