Apolipoprotein E Genotype and Sex Risk Factors for Alzheimer Disease: A Meta-analysis

IMPORTANCE: It is unclear whether female carriers of the apolipoprotein E (APOE) ε4 allele are at greater risk of developing Alzheimer disease (AD) than men, and the sex-dependent association of mild cognitive impairment (MCI) and APOE has not been established. OBJECTIVE: To determine how sex and AP...

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Veröffentlicht in:	JAMA neurology 2017-10, Vol.74 (10), p.1178-1189
Hauptverfasser:	Neu, Scott C, Pa, Judy, Kukull, Walter, Beekly, Duane, Kuzma, Amanda, Gangadharan, Prabhakaran, Wang, Li-San, Romero, Klaus, Arneric, Stephen P, Redolfi, Alberto, Orlandi, Daniele, Frisoni, Giovanni B, Au, Rhoda, Devine, Sherral, Auerbach, Sanford, Espinosa, Ana, Boada, Mercè, Ruiz, Agustín, Johnson, Sterling C, Koscik, Rebecca, Wang, Jiun-Jie, Hsu, Wen-Chuin, Chen, Yao-Liang, Toga, Arthur W
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Alzheimer Disease - epidemiology Alzheimer Disease - genetics Apolipoproteins E - genetics Case-Control Studies Databases, Factual - statistics & numerical data Female Humans Logistic Models Male Middle Aged Risk Factors Sex Characteristics
Online-Zugang:	Volltext
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