p38 Mitogen-Activated Protein Kinase is Involved in the Pathogenesis of Endometriosis by Modulating Inflammation, but not Cell Survival

Background: Local pro-inflammatory environment and enhanced cell survival contribute to the endometriosis development. A serine/threonine kinase p38 mitogen-activated protein kinase (MAPK) mediates intracellular signaling of cytokine production, cell proliferation, and apoptosis in different cell ty...

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Veröffentlicht in:	Reproductive sciences (Thousand Oaks, Calif.) Calif.), 2018-04, Vol.25 (4), p.587-597
Hauptverfasser:	Cakmak, Hakan, Seval-Celik, Yasemin, Arlier, Sefa, Guzeloglu-Kayisli, Ozlem, Schatz, Frederick, Arici, Aydin, Kayisli, Umit A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Apoptosis - physiology Cell Survival - physiology Chemokine CCL2 - metabolism Embryology Endometriosis - metabolism Endometrium - metabolism Female Humans Inflammation - metabolism Interleukin-1beta - metabolism Interleukin-8 - metabolism Medicine & Public Health Obstetrics/Perinatology/Midwifery Original Article p38 Mitogen-Activated Protein Kinases - metabolism Phosphorylation Reproductive Medicine Young Adult
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