Photoredox-Catalyzed Cascade Difluoroalkylation and Intramolecular Cyclization for Construction of Fluorinated γ‑Butyrolactones

A cascade visible-light photocatalytic difluoroalkylation and intramolecular cyclization reaction has been developed for the synthesis of difluoroalkylated oxygen heterocycles. The reaction was carried out under very mild conditions, affording fluorinated isobenzofuran-1-ones, lactone, and cyclic et...

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Veröffentlicht in:Journal of organic chemistry 2017-09, Vol.82 (18), p.9824-9831
Hauptverfasser: Sha, Wanxing, Zhang, Wenzhong, Ni, Shengyang, Mei, Haibo, Han, Jianlin, Pan, Yi
Format: Artikel
Sprache:eng
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