Circulating syndecan-1 predicts the development of disseminated intravascular coagulation in patients with sepsis

One of the pathophysiological processes in sepsis is endothelial dysfunction, which leads to disseminated intravascular coagulation (DIC). Syndecan-1 is a major structural component of the endothelium and plays a key role in endothelial function. The purpose of this study was to assess the value of...

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Veröffentlicht in:	Journal of critical care 2018-02, Vol.43, p.48-53
Hauptverfasser:	Ikeda, Mitsunori, Matsumoto, Hisatake, Ogura, Hiroshi, Hirose, Tomoya, Shimizu, Kentaro, Yamamoto, Kouji, Maruyama, Ikuro, Shimazu, Takeshi
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Anticoagulants Antithrombins APACHE Biomarkers - blood Coagulation Disseminated intravascular coagulation Disseminated Intravascular Coagulation - blood Disseminated Intravascular Coagulation - physiopathology Endothelial dysfunction Female Glycocalyx Hemodynamics Hemostatics Humans Inflammation Intensive care Male Medical prognosis Middle Aged Multiple organ dysfunction syndrome Plasminogen Activator Inhibitor 1 - blood Predictive marker Predictive Value of Tests Prospective Studies Sepsis Sepsis - blood Sepsis - physiopathology Syndecan-1 Syndecan-1 - blood Thrombosis
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