Nf1-Dependent Tumors Require a Microenvironment Containing Nf1 super(+) super(/) super(-)- and c-kit-Dependent Bone Marrow

Interactions between tumorigenic cells and their surrounding microenvironment are critical for tumor progression yet remain incompletely understood. Germline mutations in the NF1 tumor suppressor gene cause neurofibromatosis type 1 (NF1), a common genetic disorder characterized by complex tumors cal...

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Veröffentlicht in:	Cell 2008-10, Vol.135 (3), p.437-448
Hauptverfasser:	Yang, F C, Ingram, DA, Chen, S, Zhu, Y, Yuan, J, Li, X, Yang, X, Knowles, S, Horn, W, Li, Y, Zhang, S, Yang, Y, Vakili, ST, Yu, M, Burns, D, Robertson, K, Hutchins, G, Parada, L F, Clapp, D W
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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