Lamellodysidines A and B, Sesquiterpenes Isolated from the Marine Sponge Lamellodysidea herbacea

Lamellodysidines A and B, Sesquiterpenes Isolated from the Marine Sponge Lamellodysidea herbacea

Four new sesquiterpenes, lamellodysidines A and B, O,O-dimethyllingshuiolide A, and 11-epi-O,O-dimethyllingshuiolide A (1–4), were obtained from the marine sponge, Lamellodysidea herbacea, collected in Indonesia. Their planar structures were elucidated by analysis of spectroscopic data. The absolute...

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Veröffentlicht in:Journal of natural products (Washington, D.C.) D.C.), 2017-09, Vol.80 (9), p.2536-2541
Hauptverfasser: Torii, Masumi, Kato, Hikaru, Hitora, Yuki, Angkouw, Esther D, Mangindaan, Remy E. P, de Voogd, Nicole J, Tsukamoto, Sachiko
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Indonesia
Molecular Structure
Porifera - chemistry
Sesquiterpenes - chemistry
Sesquiterpenes - isolation & purification
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Zusammenfassung:Four new sesquiterpenes, lamellodysidines A and B, O,O-dimethyllingshuiolide A, and 11-epi-O,O-dimethyllingshuiolide A (1–4), were obtained from the marine sponge, Lamellodysidea herbacea, collected in Indonesia. Their planar structures were elucidated by analysis of spectroscopic data. The absolute configurations of the new compounds were determined by the calculated ECD spectra. Compound 1 has a unique carbon framework, and 2 is a new nitrogenous sesquiterpene.
ISSN:0163-3864
1520-6025
DOI:10.1021/acs.jnatprod.7b00610