Results of the first external quality assessment scheme (EQA) for isolation and analysis of circulating tumour DNA (ctDNA)

Circulating tumour DNA (ctDNA) is considered to have a high potential for future management of malignancies. This pilot external quality assessment (EQA) scheme aimed to address issues of analytical quality in this new area of laboratory diagnostics. The EQA scheme consisted of three 2-mL EDTA-plasm...

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Veröffentlicht in:	Clinical chemistry and laboratory medicine 2018-01, Vol.56 (2), p.220-228
Hauptverfasser:	Haselmann, Verena, Ahmad-Nejad, Parviz, Geilenkeuser, Wolf J., Duda, Angelika, Gabor, Merle, Eichner, Romy, Patton, Simon, Neumaier, Michael
Format:	Artikel
Sprache:	eng
Schlagworte:	Chemistry Techniques, Analytical - methods Chemistry Techniques, Analytical - standards circulating DNA Circulating Tumor DNA - analysis Circulating Tumor DNA - isolation & purification Coefficient of variation Deoxyribonucleic acid DNA Error detection Ethylenediaminetetraacetic acids external quality assessment scheme Gene frequency Genotypes Genotyping Genotyping Techniques - methods Genotyping Techniques - standards Humans Laboratories Liquid Biopsy liquid profiling Mathematical analysis Mutants plasma Plasma Volume Quality assessment Quality assurance Quality control Specimen Handling Tumors Workflow
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