Overexpression of Hypoxia-Inducible Factor 1α and p53 Is a Marker for an Unfavorable Prognosis in Gastric Cancer

Purpose: To investigate the effects of the expression of hypoxia-inducible factor 1α (HIF-1α) and p53 on the prognosis of human gastric cancer, the clinicopathologic characteristics of the tumors and the clinical outcome were analyzed. Experimental Design: The expressions of HIF-1α and p53 proteins...

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Veröffentlicht in:	Clinical cancer research 2006-09, Vol.12 (17), p.5112-5117
Hauptverfasser:	SUMIYOSHI, Yasushi, KAKEJI, Yoshihiro, EGASHIRA, Akinori, MIZOKAMI, Ken, ORITA, Hiroyuki, MAEHARA, Yoshihiko, HAMMOND, Ester M, GIACCIA, Amato J
Format:	Artikel
Sprache:	eng
Schlagworte:	angiogenesis Antineoplastic agents Biological and medical sciences gastric cancer Gastroenterology. Liver. Pancreas. Abdomen HIF-1α hypoxia Medical sciences p53 Pharmacology. Drug treatments Stomach. Duodenum. Small intestine. Colon. Rectum. Anus Tumors
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