Continuous Flow Synthesis of Morpholines and Oxazepanes with Silicon Amine Protocol (SLAP) Reagents and Lewis Acid Facilitated Photoredox Catalysis

Photocatalytic coupling of aldehydes and silicon amine protocol (SLAP) reagents enables the simple, scalable synthesis of substituted morpholines, oxazepanes, thiomorpholines, and thiazepanes under continuous flow conditions. Key to the success of this process is the combination of an inexpensive or...

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Veröffentlicht in:	Organic letters 2017-09, Vol.19 (17), p.4696-4699
Hauptverfasser:	Jackl, Moritz K, Legnani, Luca, Morandi, Bill, Bode, Jeffrey W
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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