Collaborative Action of NF-κB and p38 MAPK Is Involved in CpG DNA-Induced IFN-α and Chemokine Production in Human Plasmacytoid Dendritic Cells

CpG DNA induces plasmacytoid dendritic cells (pDC) to produce type I IFN and chemokines. However, it has not been fully elucidated how the TLR9 signaling pathway is linked to these gene expressions. We examined the mechanisms involving the TLR9 and type I IFN signaling pathways, in relation to CpG D...

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Veröffentlicht in:	Journal of Immunology 2006-10, Vol.177 (7), p.4841-4852
Hauptverfasser:	Osawa, Youko, Iho, Sumiko, Takauji, Rumiko, Takatsuka, Hisakazu, Yamamoto, Saburo, Takahashi, Takayuki, Horiguchi, Satomi, Urasaki, Yoshimasa, Matsuki, Takasumi, Fujieda, Shigeharu
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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