Mass Spectrometry Method to Measure Membrane Proteins in Dried Blood Spots for the Detection of Blood Doping Practices in Sport

The dried blood spot (DBS) matrix has significant utility for applications in the field where venous blood collection and timely shipment of labile blood samples is difficult. Unfortunately, protein measurement in DBS is hindered by high abundance proteins and matrix interference that increases with...

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Veröffentlicht in:	Analytical chemistry (Washington) 2017-09, Vol.89 (18), p.10029-10036
Hauptverfasser:	Cox, Holly D, Eichner, Daniel
Format:	Artikel
Sprache:	eng
Schlagworte:	Abundance Analyzers Blood CD45 antigen Chemistry Chromatography, Liquid Cytometry Doping Doping in Sports Dried Blood Spot Testing Erythrocytes Female Flow cytometry Healthy Volunteers Hematocrit Hematology Humans Interference Leukocytes Male Mass Spectrometry Mass spectroscopy Mathematical analysis Membrane proteins Membrane Proteins - blood Membranes Monitoring Platelets Proteins Reticulocytes Spectroscopy Sports Spots Trypsin Variation
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