Direct carboxamidation of cyclic 2-diazo-1,3-diketones by Rh2(OAc)4-catalyzed isocyanide insertion-hydrolysis

A novel and efficient strategy for the synthesis of 2-hydroxy-6-oxocyclohex-1-enecarboxamides through a Rh2(OAc)4-catalyzed direct carboxamidation of cyclic 2-diazo-1,3-diketones has been developed. The method features readily available starting materials, easy scalability, mild reaction conditions...

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Veröffentlicht in:	Organic & biomolecular chemistry 2017-08, Vol.15 (34), p.7127-7130
Hauptverfasser:	He, Xinwei, Yu, Zhiyu, Zuo, Youpeng, Yang, Cheng, Shang, Yongjia
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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