Scaling of the BMP activation gradient in Xenopus embryos

In groundbreaking experiments, Hans Spemann demonstrated that the dorsal part of the amphibian embryo can generate a well-proportioned tadpole, and that a small group of dorsal cells, the ‘organizer’, can induce a complete and well-proportioned twinned axis when transplanted into a host embryo. Key...

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Veröffentlicht in:	Nature 2008-06, Vol.453 (7199), p.1205-1211
Hauptverfasser:	Shilo, Ben-Zion, Fainsod, Abraham, Barkai, Naama, Ben-Zvi, Danny
Format:	Artikel
Sprache:	eng
Schlagworte:	Allometry Analysis Animals Biological and medical sciences Body Patterning Body Size Bone Morphogenetic Protein 4 Bone morphogenetic proteins Bone Morphogenetic Proteins - antagonists & inhibitors Bone Morphogenetic Proteins - metabolism Cell differentiation, maturation, development, hematopoiesis Cell physiology Embryo, Nonmammalian - embryology Embryo, Nonmammalian - metabolism Embryonic development Embryos Freshwater Fundamental and applied biological sciences. Psychology Glycoproteins - metabolism Humanities and Social Sciences Intercellular Signaling Peptides and Proteins - metabolism Ligands Mathematical models Measurement Mechanical properties Models, Biological Molecular and cellular biology multidisciplinary Physiological aspects Properties Protein Transport Science Science (multidisciplinary) Xenopus Xenopus - embryology Xenopus - genetics Xenopus - metabolism Xenopus Proteins - metabolism
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