Prognostic significance of CDX2 immunoexpression in poorly differentiated clusters of colorectal carcinoma

CDX2 is a transcription factor that acts as a tumor suppressor in colorectal cancer (CRC). Its loss triggers metastatic process and tumor progression; however, its prognostic role in patients with CRC is still controversial. Poorly differentiated clusters (PDCs) are aggregates of neoplastic cells wh...

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Veröffentlicht in:	Virchows Archiv : an international journal of pathology 2017-12, Vol.471 (6), p.731-741
Hauptverfasser:	Reggiani Bonetti, Luca, Lionti, Simona, Vitarelli, Enrica, Barresi, Valeria
Format:	Artikel
Sprache:	eng
Schlagworte:	Cancer CDX2 protein Clusters Colorectal cancer Colorectal carcinoma Medical prognosis Medicine Medicine & Public Health Metastases Metastasis Original Article Pathology Patients Risk groups Staining Survival Tumor suppressor genes Tumors
Online-Zugang:	Volltext
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