Chiral amplification of disodium cromoglycate chromonics induced by a codeine derivative

Chiral amplification of disodium cromoglycate chromonics induced by a codeine derivative

Chromonic liquid crystals (CLC) are lyotropic phases formed by discotic mesogens in water. Simple chiral dopants such as amino acids have been reported to turn chromonic liquid crystals into their cholesteric counterparts. Here we report a chirality amplification effect in the nematic phase of a 9 w...

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Veröffentlicht in:Soft matter 2017-10, Vol.13 (38), p.6810-6815
Hauptverfasser: Berride, F, Troche-Pesqueira, E, Feio, G, Cabrita, E J, Sierra, T, Navarro-Vázquez, A, Cid, M M
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container_end_page 6815
container_issue 38
container_start_page 6810
container_title Soft matter
container_volume 13
creator Berride, F
Troche-Pesqueira, E
Feio, G
Cabrita, E J
Sierra, T
Navarro-Vázquez, A
Cid, M M
description Chromonic liquid crystals (CLC) are lyotropic phases formed by discotic mesogens in water. Simple chiral dopants such as amino acids have been reported to turn chromonic liquid crystals into their cholesteric counterparts. Here we report a chirality amplification effect in the nematic phase of a 9 wt% disodium cromoglycate (DSCG) lyotropic liquid crystal (LLC) upon doping with a water-soluble codeine derivative. The transition on cooling the isotropic to the nematic phase showed the presence of homochiral spindle-shaped droplets (tactoids). NMR DOSY experiments on a triple gradient probe revealed a small degree of diffusion anisotropy for the alkaloid embedded in the liquid crystal structure. These results in combination with XRD, CD and POM experiments agree with a supramolecular aggregation model based on simple columnar stacks.
doi_str_mv 10.1039/c7sm01227f
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title Chiral amplification of disodium cromoglycate chromonics induced by a codeine derivative
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