Eminent Sources of Adult Mesenchymal Stem Cells and Their Therapeutic Imminence
In the recent times, stem cell biology has garnered the attention of the scientific fraternity and the general public alike due to the immense therapeutic potential that it holds in the field of regenerative medicine. A breakthrough in this direction came with the isolation of stem cells from human...
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| Veröffentlicht in: | Stem cell reviews 2017-12, Vol.13 (6), p.741-756 |
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| creator | Macrin, Dannie Joseph, Joel P. Pillai, Aruthra Arumugam Devi, Arikketh |
| description | In the recent times, stem cell biology has garnered the attention of the scientific fraternity and the general public alike due to the immense therapeutic potential that it holds in the field of regenerative medicine. A breakthrough in this direction came with the isolation of stem cells from human embryo and their differentiation into cell types of all three germ layers. However, the isolation of mesenchymal stem cells from adult tissues proved to be advantageous over embryonic stem cells due to the ethical and immunological naivety. Mesenchymal Stem Cells (MSCs) isolated from the bone marrow were found to differentiate into multiple cell lineages with the help of appropriate differentiation factors. Furthermore, other sources of stem cells including adipose tissue, dental pulp, and breast milk have been identified. Newer sources of stem cells have been emerging recently and their clinical applications are also being studied. In this review, we examine the eminent sources of Mesenchymal Stem Cells (MSCs), their immunophenotypes, and therapeutic imminence. |
| doi_str_mv | 10.1007/s12015-017-9759-8 |
| format | Article |
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In this review, we examine the eminent sources of Mesenchymal Stem Cells (MSCs), their immunophenotypes, and therapeutic imminence.</abstract><cop>New York</cop><pub>Springer US</pub><pmid>28812219</pmid><doi>10.1007/s12015-017-9759-8</doi><tpages>16</tpages></addata></record> |
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| subjects | Adipose tissue Adipose Tissue - cytology Adult Adult Stem Cells - cytology Biomedical and Life Sciences Biomedical Engineering and Bioengineering Bone marrow Breast milk Cell Biology Cell Differentiation - genetics Cell Lineage - genetics Cell- and Tissue-Based Therapy Dental pulp Dental Pulp - cytology Embryo cells Embryonic Stem Cells - cytology Embryos Ethics Humans Immunology Life Sciences Mesenchymal stem cells Mesenchymal Stem Cells - cytology Mesenchyme Regenerative Medicine Regenerative Medicine/Tissue Engineering Skin & tissue grafts Stem Cells Therapeutic applications |
| title | Eminent Sources of Adult Mesenchymal Stem Cells and Their Therapeutic Imminence |
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