The role of Melatonin receptor MTNR1A in the action of Melatonin on bovine granulosa cells

Granulosa cells (GCs) play an important role in ovarian follicle growth, development, and follicular atresia. In the present study, we investigated the effects of Melatonin on bovine GCs, and asked if MTNR1A was involved in their response to this indole hormone. Our results indicated that Melatonin...

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Veröffentlicht in:	Molecular reproduction and development 2017-11, Vol.84 (11), p.1140-1154
Hauptverfasser:	Wang, Shu‐Juan, Liu, Wen‐Ju, Wang, Li‐Ke, Pang, Xun‐Sheng, Yang, Li‐Guo
Format:	Artikel
Sprache:	eng
Schlagworte:	17β-Estradiol Activin Animals Apoptosis Apoptosis - drug effects Bcl-x protein bcl-X Protein - biosynthesis Cattle Female Gene Expression Regulation - drug effects gene regulation Glutathione Peroxidase - biosynthesis granulosa cell Granulosa cells Granulosa Cells - cytology Granulosa Cells - metabolism hormone secretion Indoles Inhibin Melatonin Melatonin - pharmacology MTNR1A p53 Protein Progesterone Receptor, Melatonin, MT1 - metabolism Receptors, LH - biosynthesis RNA interference Secretion Superoxide dismutase Superoxide Dismutase-1 - biosynthesis
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