Abortion in goats by Caprine alphaherpesvirus 1 in Spain
Contents An abortion outbreak occurred in a goat herd of Murciano‐Granadina breed in Almeria Region in Spain where 80 pregnant females aborted. All bacteriological and parasitological examinations resulted negative, whereas virological investigations and real‐time PCR assay showed the presence of Ca...
Gespeichert in:
| Veröffentlicht in: | Reproduction in domestic animals 2017-12, Vol.52 (6), p.1093-1096 |
|---|---|
| Hauptverfasser: | , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 1096 |
|---|---|
| container_issue | 6 |
| container_start_page | 1093 |
| container_title | Reproduction in domestic animals |
| container_volume | 52 |
| creator | Gonzalez, J Passantino, G Esnal, A Cuesta, N García Vera, JA Mechelli, L Saez, A García Marín, JF Tempesta, M |
| description | Contents
An abortion outbreak occurred in a goat herd of Murciano‐Granadina breed in Almeria Region in Spain where 80 pregnant females aborted. All bacteriological and parasitological examinations resulted negative, whereas virological investigations and real‐time PCR assay showed the presence of Caprine alphaherpesvirus 1 DNA in the pathological specimens from aborted foetuses. Nucleotide sequence analysis revealed that the DNA was highly close related to the Swiss strain E‐CH (99.7%) and a little less extent to the Italian BA.1 strain (99.4%). Histopathological examination revealed multifocal, well‐circumscribed, 50‐ to 200‐μm‐diameter foci of coagulative necrosis in the liver, lungs and kidneys of three foetuses. In the periphery of the necrosis, there were frequently epithelial cells with the chromatin emarginated by large, round, amphophilic intranuclear viral inclusion bodies. The source of the infection in the herd could not clearly find out even some hypothesis were formulated. This seems to be the first report of an abortion outbreak due to Caprine alphaherpesvirus 1 in a goat herd in Spain. |
| doi_str_mv | 10.1111/rda.13034 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1928785536</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1928785536</sourcerecordid><originalsourceid>FETCH-LOGICAL-c3884-c2b2c219993a743cda823ba9105f36c8ad857310d44b5a2aef7b2a6fb698b0c33</originalsourceid><addsrcrecordid>eNp10MtOwzAQBVALgWgpLPgBFIkNLNLaHsePZVWeEhISj3VkOw5NlSbBbkD9e1xaWCAxm9kcXc1chE4JHpM4E1_oMQEMbA8NCQOV4gzIPhpiBTzlgssBOgphgTHJpBCHaEClxEwJMkRyalq_qtomqZrkrdWrkJh1MtOdrxqX6Lqb67nznQsfle9DQjbsudNVc4wOSl0Hd7LbI_R6c_0yu0sfHm_vZ9OH1IKULLXUUEuJUgq0YGALLSkYrQjOSuBW6kJmAgguGDOZptqVwlDNS8OVNNgCjNDFNrfz7XvvwipfVsG6utaNa_uQE0WlkFkGPNLzP3TR9r6J10XFCQDDWEZ1uVXWtyF4V-bx16X265zgfFNnHuvMv-uM9myX2JulK37lT38RTLbgs6rd-v-k_Olquo38AnDPfB0</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1961334008</pqid></control><display><type>article</type><title>Abortion in goats by Caprine alphaherpesvirus 1 in Spain</title><source>MEDLINE</source><source>Wiley Online Library Journals Frontfile Complete</source><creator>Gonzalez, J ; Passantino, G ; Esnal, A ; Cuesta, N ; García Vera, JA ; Mechelli, L ; Saez, A ; García Marín, JF ; Tempesta, M</creator><creatorcontrib>Gonzalez, J ; Passantino, G ; Esnal, A ; Cuesta, N ; García Vera, JA ; Mechelli, L ; Saez, A ; García Marín, JF ; Tempesta, M</creatorcontrib><description>Contents
An abortion outbreak occurred in a goat herd of Murciano‐Granadina breed in Almeria Region in Spain where 80 pregnant females aborted. All bacteriological and parasitological examinations resulted negative, whereas virological investigations and real‐time PCR assay showed the presence of Caprine alphaherpesvirus 1 DNA in the pathological specimens from aborted foetuses. Nucleotide sequence analysis revealed that the DNA was highly close related to the Swiss strain E‐CH (99.7%) and a little less extent to the Italian BA.1 strain (99.4%). Histopathological examination revealed multifocal, well‐circumscribed, 50‐ to 200‐μm‐diameter foci of coagulative necrosis in the liver, lungs and kidneys of three foetuses. In the periphery of the necrosis, there were frequently epithelial cells with the chromatin emarginated by large, round, amphophilic intranuclear viral inclusion bodies. The source of the infection in the herd could not clearly find out even some hypothesis were formulated. This seems to be the first report of an abortion outbreak due to Caprine alphaherpesvirus 1 in a goat herd in Spain.</description><identifier>ISSN: 0936-6768</identifier><identifier>EISSN: 1439-0531</identifier><identifier>DOI: 10.1111/rda.13034</identifier><identifier>PMID: 28804971</identifier><language>eng</language><publisher>Germany: Blackwell Publishing Ltd</publisher><subject>Aborted Fetus - pathology ; Aborted Fetus - virology ; Abortion ; Abortion, Veterinary - epidemiology ; Abortion, Veterinary - virology ; Animals ; Caprine alphaherpesvirus 1 ; Chromatin ; Deoxyribonucleic acid ; Disease Outbreaks - veterinary ; DNA ; DNA, Viral ; Epithelial cells ; Female ; Females ; Fetuses ; Gangrene ; goat ; Goat Diseases - pathology ; Goat Diseases - virology ; Goats ; Herpesviridae Infections - pathology ; Herpesviridae Infections - veterinary ; Herpesviridae Infections - virology ; histopathology ; Inclusion bodies ; Kidneys ; Liver ; Lungs ; Necrosis ; Nucleotide sequence ; Outbreaks ; Pregnancy ; real‐time PCR ; Spain ; Spain - epidemiology ; Varicellovirus - genetics ; Varicellovirus - isolation & purification</subject><ispartof>Reproduction in domestic animals, 2017-12, Vol.52 (6), p.1093-1096</ispartof><rights>2017 Blackwell Verlag GmbH</rights><rights>2017 Blackwell Verlag GmbH.</rights><rights>Copyright © 2017 Blackwell Verlag GmbH</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3884-c2b2c219993a743cda823ba9105f36c8ad857310d44b5a2aef7b2a6fb698b0c33</citedby><cites>FETCH-LOGICAL-c3884-c2b2c219993a743cda823ba9105f36c8ad857310d44b5a2aef7b2a6fb698b0c33</cites><orcidid>0000-0003-4300-8822</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Frda.13034$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Frda.13034$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27901,27902,45550,45551</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28804971$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Gonzalez, J</creatorcontrib><creatorcontrib>Passantino, G</creatorcontrib><creatorcontrib>Esnal, A</creatorcontrib><creatorcontrib>Cuesta, N</creatorcontrib><creatorcontrib>García Vera, JA</creatorcontrib><creatorcontrib>Mechelli, L</creatorcontrib><creatorcontrib>Saez, A</creatorcontrib><creatorcontrib>García Marín, JF</creatorcontrib><creatorcontrib>Tempesta, M</creatorcontrib><title>Abortion in goats by Caprine alphaherpesvirus 1 in Spain</title><title>Reproduction in domestic animals</title><addtitle>Reprod Domest Anim</addtitle><description>Contents
An abortion outbreak occurred in a goat herd of Murciano‐Granadina breed in Almeria Region in Spain where 80 pregnant females aborted. All bacteriological and parasitological examinations resulted negative, whereas virological investigations and real‐time PCR assay showed the presence of Caprine alphaherpesvirus 1 DNA in the pathological specimens from aborted foetuses. Nucleotide sequence analysis revealed that the DNA was highly close related to the Swiss strain E‐CH (99.7%) and a little less extent to the Italian BA.1 strain (99.4%). Histopathological examination revealed multifocal, well‐circumscribed, 50‐ to 200‐μm‐diameter foci of coagulative necrosis in the liver, lungs and kidneys of three foetuses. In the periphery of the necrosis, there were frequently epithelial cells with the chromatin emarginated by large, round, amphophilic intranuclear viral inclusion bodies. The source of the infection in the herd could not clearly find out even some hypothesis were formulated. This seems to be the first report of an abortion outbreak due to Caprine alphaherpesvirus 1 in a goat herd in Spain.</description><subject>Aborted Fetus - pathology</subject><subject>Aborted Fetus - virology</subject><subject>Abortion</subject><subject>Abortion, Veterinary - epidemiology</subject><subject>Abortion, Veterinary - virology</subject><subject>Animals</subject><subject>Caprine alphaherpesvirus 1</subject><subject>Chromatin</subject><subject>Deoxyribonucleic acid</subject><subject>Disease Outbreaks - veterinary</subject><subject>DNA</subject><subject>DNA, Viral</subject><subject>Epithelial cells</subject><subject>Female</subject><subject>Females</subject><subject>Fetuses</subject><subject>Gangrene</subject><subject>goat</subject><subject>Goat Diseases - pathology</subject><subject>Goat Diseases - virology</subject><subject>Goats</subject><subject>Herpesviridae Infections - pathology</subject><subject>Herpesviridae Infections - veterinary</subject><subject>Herpesviridae Infections - virology</subject><subject>histopathology</subject><subject>Inclusion bodies</subject><subject>Kidneys</subject><subject>Liver</subject><subject>Lungs</subject><subject>Necrosis</subject><subject>Nucleotide sequence</subject><subject>Outbreaks</subject><subject>Pregnancy</subject><subject>real‐time PCR</subject><subject>Spain</subject><subject>Spain - epidemiology</subject><subject>Varicellovirus - genetics</subject><subject>Varicellovirus - isolation & purification</subject><issn>0936-6768</issn><issn>1439-0531</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp10MtOwzAQBVALgWgpLPgBFIkNLNLaHsePZVWeEhISj3VkOw5NlSbBbkD9e1xaWCAxm9kcXc1chE4JHpM4E1_oMQEMbA8NCQOV4gzIPhpiBTzlgssBOgphgTHJpBCHaEClxEwJMkRyalq_qtomqZrkrdWrkJh1MtOdrxqX6Lqb67nznQsfle9DQjbsudNVc4wOSl0Hd7LbI_R6c_0yu0sfHm_vZ9OH1IKULLXUUEuJUgq0YGALLSkYrQjOSuBW6kJmAgguGDOZptqVwlDNS8OVNNgCjNDFNrfz7XvvwipfVsG6utaNa_uQE0WlkFkGPNLzP3TR9r6J10XFCQDDWEZ1uVXWtyF4V-bx16X265zgfFNnHuvMv-uM9myX2JulK37lT38RTLbgs6rd-v-k_Olquo38AnDPfB0</recordid><startdate>201712</startdate><enddate>201712</enddate><creator>Gonzalez, J</creator><creator>Passantino, G</creator><creator>Esnal, A</creator><creator>Cuesta, N</creator><creator>García Vera, JA</creator><creator>Mechelli, L</creator><creator>Saez, A</creator><creator>García Marín, JF</creator><creator>Tempesta, M</creator><general>Blackwell Publishing Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QO</scope><scope>8FD</scope><scope>FR3</scope><scope>P64</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0003-4300-8822</orcidid></search><sort><creationdate>201712</creationdate><title>Abortion in goats by Caprine alphaherpesvirus 1 in Spain</title><author>Gonzalez, J ; Passantino, G ; Esnal, A ; Cuesta, N ; García Vera, JA ; Mechelli, L ; Saez, A ; García Marín, JF ; Tempesta, M</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3884-c2b2c219993a743cda823ba9105f36c8ad857310d44b5a2aef7b2a6fb698b0c33</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Aborted Fetus - pathology</topic><topic>Aborted Fetus - virology</topic><topic>Abortion</topic><topic>Abortion, Veterinary - epidemiology</topic><topic>Abortion, Veterinary - virology</topic><topic>Animals</topic><topic>Caprine alphaherpesvirus 1</topic><topic>Chromatin</topic><topic>Deoxyribonucleic acid</topic><topic>Disease Outbreaks - veterinary</topic><topic>DNA</topic><topic>DNA, Viral</topic><topic>Epithelial cells</topic><topic>Female</topic><topic>Females</topic><topic>Fetuses</topic><topic>Gangrene</topic><topic>goat</topic><topic>Goat Diseases - pathology</topic><topic>Goat Diseases - virology</topic><topic>Goats</topic><topic>Herpesviridae Infections - pathology</topic><topic>Herpesviridae Infections - veterinary</topic><topic>Herpesviridae Infections - virology</topic><topic>histopathology</topic><topic>Inclusion bodies</topic><topic>Kidneys</topic><topic>Liver</topic><topic>Lungs</topic><topic>Necrosis</topic><topic>Nucleotide sequence</topic><topic>Outbreaks</topic><topic>Pregnancy</topic><topic>real‐time PCR</topic><topic>Spain</topic><topic>Spain - epidemiology</topic><topic>Varicellovirus - genetics</topic><topic>Varicellovirus - isolation & purification</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Gonzalez, J</creatorcontrib><creatorcontrib>Passantino, G</creatorcontrib><creatorcontrib>Esnal, A</creatorcontrib><creatorcontrib>Cuesta, N</creatorcontrib><creatorcontrib>García Vera, JA</creatorcontrib><creatorcontrib>Mechelli, L</creatorcontrib><creatorcontrib>Saez, A</creatorcontrib><creatorcontrib>García Marín, JF</creatorcontrib><creatorcontrib>Tempesta, M</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Biotechnology Research Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Reproduction in domestic animals</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Gonzalez, J</au><au>Passantino, G</au><au>Esnal, A</au><au>Cuesta, N</au><au>García Vera, JA</au><au>Mechelli, L</au><au>Saez, A</au><au>García Marín, JF</au><au>Tempesta, M</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Abortion in goats by Caprine alphaherpesvirus 1 in Spain</atitle><jtitle>Reproduction in domestic animals</jtitle><addtitle>Reprod Domest Anim</addtitle><date>2017-12</date><risdate>2017</risdate><volume>52</volume><issue>6</issue><spage>1093</spage><epage>1096</epage><pages>1093-1096</pages><issn>0936-6768</issn><eissn>1439-0531</eissn><abstract>Contents
An abortion outbreak occurred in a goat herd of Murciano‐Granadina breed in Almeria Region in Spain where 80 pregnant females aborted. All bacteriological and parasitological examinations resulted negative, whereas virological investigations and real‐time PCR assay showed the presence of Caprine alphaherpesvirus 1 DNA in the pathological specimens from aborted foetuses. Nucleotide sequence analysis revealed that the DNA was highly close related to the Swiss strain E‐CH (99.7%) and a little less extent to the Italian BA.1 strain (99.4%). Histopathological examination revealed multifocal, well‐circumscribed, 50‐ to 200‐μm‐diameter foci of coagulative necrosis in the liver, lungs and kidneys of three foetuses. In the periphery of the necrosis, there were frequently epithelial cells with the chromatin emarginated by large, round, amphophilic intranuclear viral inclusion bodies. The source of the infection in the herd could not clearly find out even some hypothesis were formulated. This seems to be the first report of an abortion outbreak due to Caprine alphaherpesvirus 1 in a goat herd in Spain.</abstract><cop>Germany</cop><pub>Blackwell Publishing Ltd</pub><pmid>28804971</pmid><doi>10.1111/rda.13034</doi><tpages>4</tpages><orcidid>https://orcid.org/0000-0003-4300-8822</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0936-6768 |
| ispartof | Reproduction in domestic animals, 2017-12, Vol.52 (6), p.1093-1096 |
| issn | 0936-6768 1439-0531 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1928785536 |
| source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
| subjects | Aborted Fetus - pathology Aborted Fetus - virology Abortion Abortion, Veterinary - epidemiology Abortion, Veterinary - virology Animals Caprine alphaherpesvirus 1 Chromatin Deoxyribonucleic acid Disease Outbreaks - veterinary DNA DNA, Viral Epithelial cells Female Females Fetuses Gangrene goat Goat Diseases - pathology Goat Diseases - virology Goats Herpesviridae Infections - pathology Herpesviridae Infections - veterinary Herpesviridae Infections - virology histopathology Inclusion bodies Kidneys Liver Lungs Necrosis Nucleotide sequence Outbreaks Pregnancy real‐time PCR Spain Spain - epidemiology Varicellovirus - genetics Varicellovirus - isolation & purification |
| title | Abortion in goats by Caprine alphaherpesvirus 1 in Spain |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-14T11%3A12%3A54IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Abortion%20in%20goats%20by%20Caprine%20alphaherpesvirus%201%20in%20Spain&rft.jtitle=Reproduction%20in%20domestic%20animals&rft.au=Gonzalez,%20J&rft.date=2017-12&rft.volume=52&rft.issue=6&rft.spage=1093&rft.epage=1096&rft.pages=1093-1096&rft.issn=0936-6768&rft.eissn=1439-0531&rft_id=info:doi/10.1111/rda.13034&rft_dat=%3Cproquest_cross%3E1928785536%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1961334008&rft_id=info:pmid/28804971&rfr_iscdi=true |