20-Hydroxyecdysone attenuates cardiac remodeling in spontaneously hypertensive rats

[Display omitted] •20-HE significantly reduces systolic blood pressure in SHR rats.•20-HE significantly attenuates dilated cardiac hypertrophy in SHR rats.•20-HE significantly upregulates the expression of cardiac β-MHC isoform in SHR rats. Ecdysteroids, a group of steroid hormones found in insects...

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Veröffentlicht in:	Steroids 2017-10, Vol.126, p.79-84
Hauptverfasser:	Phungphong, Sukanya, Kijtawornrat, Anusak, Chaiduang, Sirinut, Saengsirisuwan, Vitoon, Bupha-Intr, Tepmanas
Format:	Artikel
Sprache:	eng
Schlagworte:	20-Hydroxyecdysone Animals Arterial blood pressure Blood Pressure - drug effects Cardiomyocyte Ecdysterone - pharmacology Echocardiography Heart - drug effects Heart - physiology Heart - physiopathology Male Myocardium - pathology Myosin heavy chain Rats Rats, Inbred SHR
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