Treatment of Unstable Thoracolumbar Fractures: Does Fracture-Level Fixation Accelerate the Bone Healing?
To investigate the effect of fusion on short segment including fractured level (SSIFL) and long segment (LS) transpedicular fixation after acute thoracolumbar junction burst fractures. The 2-year clinical and radiologic follow-up results of the 2 groups also were compared. Seventy-four patients were...
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Veröffentlicht in: | World neurosurgery 2017-11, Vol.107, p.362-370 |
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description | To investigate the effect of fusion on short segment including fractured level (SSIFL) and long segment (LS) transpedicular fixation after acute thoracolumbar junction burst fractures. The 2-year clinical and radiologic follow-up results of the 2 groups also were compared.
Seventy-four patients were randomized into one of 2 groups: SSIFL (n = 39) or LS (n = 35). The SSIFL group included one level above and one level below, including the fracture level, whereas the LS group included 2 levels above and 2 levels below, excluding the fracture level, for the transpedicular fixation. Fusion was assessed by technetium 99m-methylendiphosphonate, bone scintigraphy, and single-photon emission computed tomography. The 2-year follow-up results were compared clinically (Oswestry Disability Index and visual analog scale) and radiologically (kyphosis angle, sagittal index, anterior vertebral body height loss) at regular intervals. The clinical scores and radiologic parameters of patients with and without fusion also were compared.
The number of patients with fusion was significantly greater in the SSIFL group compared with the LS group. There was a significant reduction of the clinical scores of patients who had fusion compared with the fusion-free group; however, there was no radiologically significant difference. Furthermore, there was no significant difference between the SSIFL and LS groups in terms of the 2-year radiologic and clinical follow-up results.
Fusion occurred sooner and patients experienced earlier clinical recovery in the SSIFL group compared with the LS group. |
doi_str_mv | 10.1016/j.wneu.2017.08.007 |
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Seventy-four patients were randomized into one of 2 groups: SSIFL (n = 39) or LS (n = 35). The SSIFL group included one level above and one level below, including the fracture level, whereas the LS group included 2 levels above and 2 levels below, excluding the fracture level, for the transpedicular fixation. Fusion was assessed by technetium 99m-methylendiphosphonate, bone scintigraphy, and single-photon emission computed tomography. The 2-year follow-up results were compared clinically (Oswestry Disability Index and visual analog scale) and radiologically (kyphosis angle, sagittal index, anterior vertebral body height loss) at regular intervals. The clinical scores and radiologic parameters of patients with and without fusion also were compared.
The number of patients with fusion was significantly greater in the SSIFL group compared with the LS group. There was a significant reduction of the clinical scores of patients who had fusion compared with the fusion-free group; however, there was no radiologically significant difference. Furthermore, there was no significant difference between the SSIFL and LS groups in terms of the 2-year radiologic and clinical follow-up results.
Fusion occurred sooner and patients experienced earlier clinical recovery in the SSIFL group compared with the LS group.</description><identifier>ISSN: 1878-8750</identifier><identifier>EISSN: 1878-8769</identifier><identifier>DOI: 10.1016/j.wneu.2017.08.007</identifier><identifier>PMID: 28803178</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Adult ; Female ; Follow-Up Studies ; Fracture ; Fracture Fixation, Internal - methods ; Fracture Healing - physiology ; Fusion ; Humans ; Long segment ; Lumbar Vertebrae - diagnostic imaging ; Lumbar Vertebrae - injuries ; Lumbar Vertebrae - surgery ; Male ; Middle Aged ; Prospective Studies ; Short segment ; Smoking - adverse effects ; Spinal Fractures - diagnostic imaging ; Spinal Fractures - surgery ; Thoracic Vertebrae - diagnostic imaging ; Thoracic Vertebrae - injuries ; Thoracic Vertebrae - surgery ; Thoracolumbar ; Treatment Outcome</subject><ispartof>World neurosurgery, 2017-11, Vol.107, p.362-370</ispartof><rights>2017 Elsevier Inc.</rights><rights>Copyright © 2017 Elsevier Inc. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c356t-99dee895468432e1a4151449ebd0028fd44aaeba2873bf8ec10f5331db38000d3</citedby><cites>FETCH-LOGICAL-c356t-99dee895468432e1a4151449ebd0028fd44aaeba2873bf8ec10f5331db38000d3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.wneu.2017.08.007$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>315,781,785,3551,27929,27930,46000</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28803178$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Özbek, Zühtü</creatorcontrib><creatorcontrib>Özkara, Emre</creatorcontrib><creatorcontrib>Önner, Hasan</creatorcontrib><creatorcontrib>BAŞ, Gültekin</creatorcontrib><creatorcontrib>Erman, İpek Canan</creatorcontrib><creatorcontrib>Özen, Hülya</creatorcontrib><creatorcontrib>Entok, Emre</creatorcontrib><creatorcontrib>Arslantaş, Ali</creatorcontrib><title>Treatment of Unstable Thoracolumbar Fractures: Does Fracture-Level Fixation Accelerate the Bone Healing?</title><title>World neurosurgery</title><addtitle>World Neurosurg</addtitle><description>To investigate the effect of fusion on short segment including fractured level (SSIFL) and long segment (LS) transpedicular fixation after acute thoracolumbar junction burst fractures. The 2-year clinical and radiologic follow-up results of the 2 groups also were compared.
Seventy-four patients were randomized into one of 2 groups: SSIFL (n = 39) or LS (n = 35). The SSIFL group included one level above and one level below, including the fracture level, whereas the LS group included 2 levels above and 2 levels below, excluding the fracture level, for the transpedicular fixation. Fusion was assessed by technetium 99m-methylendiphosphonate, bone scintigraphy, and single-photon emission computed tomography. The 2-year follow-up results were compared clinically (Oswestry Disability Index and visual analog scale) and radiologically (kyphosis angle, sagittal index, anterior vertebral body height loss) at regular intervals. The clinical scores and radiologic parameters of patients with and without fusion also were compared.
The number of patients with fusion was significantly greater in the SSIFL group compared with the LS group. There was a significant reduction of the clinical scores of patients who had fusion compared with the fusion-free group; however, there was no radiologically significant difference. Furthermore, there was no significant difference between the SSIFL and LS groups in terms of the 2-year radiologic and clinical follow-up results.
Fusion occurred sooner and patients experienced earlier clinical recovery in the SSIFL group compared with the LS group.</description><subject>Adult</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Fracture</subject><subject>Fracture Fixation, Internal - methods</subject><subject>Fracture Healing - physiology</subject><subject>Fusion</subject><subject>Humans</subject><subject>Long segment</subject><subject>Lumbar Vertebrae - diagnostic imaging</subject><subject>Lumbar Vertebrae - injuries</subject><subject>Lumbar Vertebrae - surgery</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Prospective Studies</subject><subject>Short segment</subject><subject>Smoking - adverse effects</subject><subject>Spinal Fractures - diagnostic imaging</subject><subject>Spinal Fractures - surgery</subject><subject>Thoracic Vertebrae - diagnostic imaging</subject><subject>Thoracic Vertebrae - injuries</subject><subject>Thoracic Vertebrae - surgery</subject><subject>Thoracolumbar</subject><subject>Treatment Outcome</subject><issn>1878-8750</issn><issn>1878-8769</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kM1OwzAQhC0EohXwAhyQj1wS7MRJHISEyk8pUiUu7dlynA11lcTFdgq8Pa4KPeKLd6WZ0c6H0CUlMSU0v1nHnz0McUJoERMeE1IcoTHlBY94kZfHhzkjI3Th3JqEl1LGi_QUjRLOw1LwMVotLEjfQe-xafCyd15WLeDFylipTDt0lbR4GmY_WHC3-MmAO-zRHLbQ4qn-kl6bHk-Ughas9ID9CvCD6QHPQLa6f78_RyeNbB1c_P5naDl9XjzOovnby-vjZB6pNMt9VJY1AC8zlnOWJkAloxllrISqJiThTc2YlFDJJBSpGg6KkiZLU1pXKQ8N6_QMXe9zN9Z8DOC86LQLZ7WyBzM4Qctg5QnL8iBN9lJljXMWGrGxupP2W1AidpDFWuwgix1kQbgIkIPp6jd_qDqoD5Y_pEFwtxdAaLnVYIVTGnoFtbagvKiN_i__BzX8jeQ</recordid><startdate>201711</startdate><enddate>201711</enddate><creator>Özbek, Zühtü</creator><creator>Özkara, Emre</creator><creator>Önner, Hasan</creator><creator>BAŞ, Gültekin</creator><creator>Erman, İpek Canan</creator><creator>Özen, Hülya</creator><creator>Entok, Emre</creator><creator>Arslantaş, Ali</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>201711</creationdate><title>Treatment of Unstable Thoracolumbar Fractures: Does Fracture-Level Fixation Accelerate the Bone Healing?</title><author>Özbek, Zühtü ; Özkara, Emre ; Önner, Hasan ; BAŞ, Gültekin ; Erman, İpek Canan ; Özen, Hülya ; Entok, Emre ; Arslantaş, Ali</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c356t-99dee895468432e1a4151449ebd0028fd44aaeba2873bf8ec10f5331db38000d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Adult</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Fracture</topic><topic>Fracture Fixation, Internal - methods</topic><topic>Fracture Healing - physiology</topic><topic>Fusion</topic><topic>Humans</topic><topic>Long segment</topic><topic>Lumbar Vertebrae - diagnostic imaging</topic><topic>Lumbar Vertebrae - injuries</topic><topic>Lumbar Vertebrae - surgery</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Prospective Studies</topic><topic>Short segment</topic><topic>Smoking - adverse effects</topic><topic>Spinal Fractures - diagnostic imaging</topic><topic>Spinal Fractures - surgery</topic><topic>Thoracic Vertebrae - diagnostic imaging</topic><topic>Thoracic Vertebrae - injuries</topic><topic>Thoracic Vertebrae - surgery</topic><topic>Thoracolumbar</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Özbek, Zühtü</creatorcontrib><creatorcontrib>Özkara, Emre</creatorcontrib><creatorcontrib>Önner, Hasan</creatorcontrib><creatorcontrib>BAŞ, Gültekin</creatorcontrib><creatorcontrib>Erman, İpek Canan</creatorcontrib><creatorcontrib>Özen, Hülya</creatorcontrib><creatorcontrib>Entok, Emre</creatorcontrib><creatorcontrib>Arslantaş, Ali</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>World neurosurgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Özbek, Zühtü</au><au>Özkara, Emre</au><au>Önner, Hasan</au><au>BAŞ, Gültekin</au><au>Erman, İpek Canan</au><au>Özen, Hülya</au><au>Entok, Emre</au><au>Arslantaş, Ali</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Treatment of Unstable Thoracolumbar Fractures: Does Fracture-Level Fixation Accelerate the Bone Healing?</atitle><jtitle>World neurosurgery</jtitle><addtitle>World Neurosurg</addtitle><date>2017-11</date><risdate>2017</risdate><volume>107</volume><spage>362</spage><epage>370</epage><pages>362-370</pages><issn>1878-8750</issn><eissn>1878-8769</eissn><abstract>To investigate the effect of fusion on short segment including fractured level (SSIFL) and long segment (LS) transpedicular fixation after acute thoracolumbar junction burst fractures. The 2-year clinical and radiologic follow-up results of the 2 groups also were compared.
Seventy-four patients were randomized into one of 2 groups: SSIFL (n = 39) or LS (n = 35). The SSIFL group included one level above and one level below, including the fracture level, whereas the LS group included 2 levels above and 2 levels below, excluding the fracture level, for the transpedicular fixation. Fusion was assessed by technetium 99m-methylendiphosphonate, bone scintigraphy, and single-photon emission computed tomography. The 2-year follow-up results were compared clinically (Oswestry Disability Index and visual analog scale) and radiologically (kyphosis angle, sagittal index, anterior vertebral body height loss) at regular intervals. The clinical scores and radiologic parameters of patients with and without fusion also were compared.
The number of patients with fusion was significantly greater in the SSIFL group compared with the LS group. There was a significant reduction of the clinical scores of patients who had fusion compared with the fusion-free group; however, there was no radiologically significant difference. Furthermore, there was no significant difference between the SSIFL and LS groups in terms of the 2-year radiologic and clinical follow-up results.
Fusion occurred sooner and patients experienced earlier clinical recovery in the SSIFL group compared with the LS group.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>28803178</pmid><doi>10.1016/j.wneu.2017.08.007</doi><tpages>9</tpages></addata></record> |
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subjects | Adult Female Follow-Up Studies Fracture Fracture Fixation, Internal - methods Fracture Healing - physiology Fusion Humans Long segment Lumbar Vertebrae - diagnostic imaging Lumbar Vertebrae - injuries Lumbar Vertebrae - surgery Male Middle Aged Prospective Studies Short segment Smoking - adverse effects Spinal Fractures - diagnostic imaging Spinal Fractures - surgery Thoracic Vertebrae - diagnostic imaging Thoracic Vertebrae - injuries Thoracic Vertebrae - surgery Thoracolumbar Treatment Outcome |
title | Treatment of Unstable Thoracolumbar Fractures: Does Fracture-Level Fixation Accelerate the Bone Healing? |
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