Distribution of HLA-A, -B and -DRB1 antigenic groups and haplotypes from the Brazilian bone marrow donor registry (REDOME)

To improve assistance for patients awaiting a bone marrow transplant from an unrelated donor, it is important to genetically characterize the Brazilian volunteer bone marrow donors registry (REDOME). Our objective was to describe the antigenic groups and haplotype frequencies of HLA-A, HLA-B and HLA...

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Veröffentlicht in:	Human immunology 2017-10, Vol.78 (10), p.602-609
Hauptverfasser:	Torres, Leandro, da Silva Bouzas, Luis Fernando, Almada, Alexandre, de Sobrino Porto, Luis Cristovão Moraes, Abdelhay, Eliana
Format:	Artikel
Sprache:	eng
Schlagworte:	Bone marrow transplant Bone Marrow Transplantation Brazil Donor registry Ethnic Groups Expectation-maximization Gene Frequency Genotype Haplotype frequency estimation HLA haplotypes HLA-A Antigens - genetics HLA-B Antigens - genetics HLA-DRB1 Chains - genetics Human leukocyte antigen Humans Principal Component Analysis Registries Resource Allocation Tissue Donors Volunteers
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