Using Chemistry to Target Neuroblastoma

Neuroblastoma is a cancer of the neural crest almost exclusively seen in childhood. While children with single, small primary tumors are often cured with surgery alone, the 65% of children with neuroblastoma whose disease has metastasized have less than a 50% chance of surviving five years after dia...

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Veröffentlicht in:	ACS chemical neuroscience 2017-10, Vol.8 (10), p.2118-2123
Hauptverfasser:	Hansen, Jeanne N, Li, Xingguo, Zheng, Y. George, Lotta, Louis T, Dedhe, Abhishek, Schor, Nina F
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Arginine - analogs & derivatives Arginine - chemistry Humans Neural Crest - metabolism Neuroblastoma - pathology Neuroblastoma - surgery Oncogene Proteins - metabolism Reactive Oxygen Species - metabolism Signal Transduction - physiology
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