Nerves, H2O2 and Shh: Three players in the game of regeneration

The tight control of reactive oxygen species (ROS) levels is required during regeneration. H2O2 in particular assumes clear signalling functions at different steps in this process. Injured nerves induce high levels of H2O2 through the activation of the Hedgehog (Shh) pathway, providing an environmen...

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Veröffentlicht in:Seminars in cell & developmental biology 2018-08, Vol.80, p.65-73
Hauptverfasser: Meda, Francesca, Rampon, Christine, Dupont, Edmond, Gauron, Carole, Mourton, Aurélien, Queguiner, Isabelle, Thauvin, Marion, Volovitch, Michel, Joliot, Alain, Vriz, Sophie
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Sprache:eng
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