Biosynthesis and combinatorial biosynthesis of antifungal nucleoside antibiotics

There is an urgent need for new antifungal agents to treat or combat fungal infection in humans and plants.Antifungal nucleoside antibiotics are an important family of natural products with distinctive structural features.Understanding their biosynthetic machinery is of great importance for the impr...

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Veröffentlicht in:	Science China. Life sciences 2017-09, Vol.60 (9), p.939-947
Hauptverfasser:	Niu, Guoqing, Zheng, Jiazhen, Tan, Huarong
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibiotics Antifungal agents Antifungal Agents - chemistry Antifungal Agents - metabolism Biomedical and Life Sciences Biosynthesis Biosynthetic Pathways Life Sciences Metabolic Engineering Natural products Nucleosides - biosynthesis Nucleosides - chemistry Nucleosides - genetics Review 天然产品家庭抗真菌核苷类抗生素真菌感染组合生物合成结构特征药物治疗
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