Monitoring wound healing in minor burns—A novel approach
•The use of bioimpedance spectroscopy (BIS) for monitoring wound healing is explored.•BIS resistance measures can be used to monitor burn wound healing.•BIS phase angle should have further investigation in the assessment of acute burn wound healing. Assessment of minor burn wound closure is predomin...
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Veröffentlicht in: | Burns 2018-02, Vol.44 (1), p.70-76 |
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creator | Kenworthy, Pippa Phillips, Michael Grisbrook, Tiffany L. Gibson, William Wood, Fiona M. Edgar, Dale W. |
description | •The use of bioimpedance spectroscopy (BIS) for monitoring wound healing is explored.•BIS resistance measures can be used to monitor burn wound healing.•BIS phase angle should have further investigation in the assessment of acute burn wound healing.
Assessment of minor burn wound closure is predominately determined by visual inspection and clinical specialist assessment, which remains largely a subjective analysis and results may vary depending on the clinician’s experience. Bioimpedance spectroscopy (BIS) is an instrument that has a demonstrated ability to objectively monitor the wound healing process in various patient populations but has not yet been used in acute burn wounds.
The aim of the pilot study was to examine whether the BIS technique is a valid measure of wound healing.
Localised BIS resistance and phase angle triplicate measures, of minor limb burns, were collected on two serial occasions. Circumference limb measures were taken at the localised burn site to determine a truncated limb volume. Proportional-odds ordered logistic regression analyses determined resistance at zero frequency (R0, indicative of edema) and resistance of total body fluid (Rinf) were significantly associated with healing after adjustment for the influence of surgery. A one unit increase in R0 and Rinf increased the odds of wound healing by 6% and 5% respectively (p |
doi_str_mv | 10.1016/j.burns.2017.06.007 |
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Assessment of minor burn wound closure is predominately determined by visual inspection and clinical specialist assessment, which remains largely a subjective analysis and results may vary depending on the clinician’s experience. Bioimpedance spectroscopy (BIS) is an instrument that has a demonstrated ability to objectively monitor the wound healing process in various patient populations but has not yet been used in acute burn wounds.
The aim of the pilot study was to examine whether the BIS technique is a valid measure of wound healing.
Localised BIS resistance and phase angle triplicate measures, of minor limb burns, were collected on two serial occasions. Circumference limb measures were taken at the localised burn site to determine a truncated limb volume. Proportional-odds ordered logistic regression analyses determined resistance at zero frequency (R0, indicative of edema) and resistance of total body fluid (Rinf) were significantly associated with healing after adjustment for the influence of surgery. A one unit increase in R0 and Rinf increased the odds of wound healing by 6% and 5% respectively (p<0.01). Phase angle at 50kHz and Ri were not significantly associated with the markers of the wound healing process. Spearman’s correlation determined there was a significant association between a healing wound and limb segment volume (ml) (rho −0.30, p<0.01). BIS is a technique, which has the potential to monitor the progress of wound healing.</description><identifier>ISSN: 0305-4179</identifier><identifier>EISSN: 1879-1409</identifier><identifier>DOI: 10.1016/j.burns.2017.06.007</identifier><identifier>PMID: 28784342</identifier><language>eng</language><publisher>Netherlands: Elsevier Ltd</publisher><subject>Adult ; Bioelectrical impedance ; Bioimpedance spectroscopy ; Burns - diagnosis ; Burns - pathology ; Dielectric Spectroscopy ; Female ; Humans ; Logistic Models ; Male ; Phase angle ; Pilot Projects ; Resistance ; Spectrum Analysis ; Wound assessment ; Wound Healing ; Young Adult</subject><ispartof>Burns, 2018-02, Vol.44 (1), p.70-76</ispartof><rights>2017</rights><rights>Crown Copyright © 2017. Published by Elsevier Ltd. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c359t-d1187b0aa3499825608d7b2885424c89c908166275e04edd39214805e73d0a393</citedby><cites>FETCH-LOGICAL-c359t-d1187b0aa3499825608d7b2885424c89c908166275e04edd39214805e73d0a393</cites><orcidid>0000-0002-7559-6051</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0305417917303595$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28784342$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kenworthy, Pippa</creatorcontrib><creatorcontrib>Phillips, Michael</creatorcontrib><creatorcontrib>Grisbrook, Tiffany L.</creatorcontrib><creatorcontrib>Gibson, William</creatorcontrib><creatorcontrib>Wood, Fiona M.</creatorcontrib><creatorcontrib>Edgar, Dale W.</creatorcontrib><title>Monitoring wound healing in minor burns—A novel approach</title><title>Burns</title><addtitle>Burns</addtitle><description>•The use of bioimpedance spectroscopy (BIS) for monitoring wound healing is explored.•BIS resistance measures can be used to monitor burn wound healing.•BIS phase angle should have further investigation in the assessment of acute burn wound healing.
Assessment of minor burn wound closure is predominately determined by visual inspection and clinical specialist assessment, which remains largely a subjective analysis and results may vary depending on the clinician’s experience. Bioimpedance spectroscopy (BIS) is an instrument that has a demonstrated ability to objectively monitor the wound healing process in various patient populations but has not yet been used in acute burn wounds.
The aim of the pilot study was to examine whether the BIS technique is a valid measure of wound healing.
Localised BIS resistance and phase angle triplicate measures, of minor limb burns, were collected on two serial occasions. Circumference limb measures were taken at the localised burn site to determine a truncated limb volume. Proportional-odds ordered logistic regression analyses determined resistance at zero frequency (R0, indicative of edema) and resistance of total body fluid (Rinf) were significantly associated with healing after adjustment for the influence of surgery. A one unit increase in R0 and Rinf increased the odds of wound healing by 6% and 5% respectively (p<0.01). Phase angle at 50kHz and Ri were not significantly associated with the markers of the wound healing process. Spearman’s correlation determined there was a significant association between a healing wound and limb segment volume (ml) (rho −0.30, p<0.01). BIS is a technique, which has the potential to monitor the progress of wound healing.</description><subject>Adult</subject><subject>Bioelectrical impedance</subject><subject>Bioimpedance spectroscopy</subject><subject>Burns - diagnosis</subject><subject>Burns - pathology</subject><subject>Dielectric Spectroscopy</subject><subject>Female</subject><subject>Humans</subject><subject>Logistic Models</subject><subject>Male</subject><subject>Phase angle</subject><subject>Pilot Projects</subject><subject>Resistance</subject><subject>Spectrum Analysis</subject><subject>Wound assessment</subject><subject>Wound Healing</subject><subject>Young Adult</subject><issn>0305-4179</issn><issn>1879-1409</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kMtKBDEQRYMoOj6-QJBeuum28uhOIrgQ8QWKG12HTBI1Q08yJtMj7vwIv9AvMeOoS2tTFNyqU_citI-hwYC7o0kzHlLIDQHMG-gaAL6GRlhwWWMGch2NgEJbM8zlFtrOeQKlWgGbaIsILhhlZISOb2Pw85h8eKpe4xBs9ex0v5x8qKY-xFR9Uz7fP06rEBeur_RslqI2z7to41H32e399B30cHF-f3ZV39xdXp-d3tSGtnJeW1xeGoPWlEkpSNuBsHxMhGgZYUZII0HgriO8dcCctVQSzAS0jlMLmkq6gw5Xdwv2ZXB5rqY-G9f3Org4ZIUl4cUoI6RI6UpqUsw5uUc1S36q05vCoJahqYn6tqOWoSnoVAmtbB38AIbx1Nm_nd-UiuBkJXDF5sK7pLLxLhhnfXJmrmz0_wK-AFFwfWs</recordid><startdate>201802</startdate><enddate>201802</enddate><creator>Kenworthy, Pippa</creator><creator>Phillips, Michael</creator><creator>Grisbrook, Tiffany L.</creator><creator>Gibson, William</creator><creator>Wood, Fiona M.</creator><creator>Edgar, Dale W.</creator><general>Elsevier Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-7559-6051</orcidid></search><sort><creationdate>201802</creationdate><title>Monitoring wound healing in minor burns—A novel approach</title><author>Kenworthy, Pippa ; Phillips, Michael ; Grisbrook, Tiffany L. ; Gibson, William ; Wood, Fiona M. ; Edgar, Dale W.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c359t-d1187b0aa3499825608d7b2885424c89c908166275e04edd39214805e73d0a393</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><topic>Adult</topic><topic>Bioelectrical impedance</topic><topic>Bioimpedance spectroscopy</topic><topic>Burns - diagnosis</topic><topic>Burns - pathology</topic><topic>Dielectric Spectroscopy</topic><topic>Female</topic><topic>Humans</topic><topic>Logistic Models</topic><topic>Male</topic><topic>Phase angle</topic><topic>Pilot Projects</topic><topic>Resistance</topic><topic>Spectrum Analysis</topic><topic>Wound assessment</topic><topic>Wound Healing</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kenworthy, Pippa</creatorcontrib><creatorcontrib>Phillips, Michael</creatorcontrib><creatorcontrib>Grisbrook, Tiffany L.</creatorcontrib><creatorcontrib>Gibson, William</creatorcontrib><creatorcontrib>Wood, Fiona M.</creatorcontrib><creatorcontrib>Edgar, Dale W.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Burns</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kenworthy, Pippa</au><au>Phillips, Michael</au><au>Grisbrook, Tiffany L.</au><au>Gibson, William</au><au>Wood, Fiona M.</au><au>Edgar, Dale W.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Monitoring wound healing in minor burns—A novel approach</atitle><jtitle>Burns</jtitle><addtitle>Burns</addtitle><date>2018-02</date><risdate>2018</risdate><volume>44</volume><issue>1</issue><spage>70</spage><epage>76</epage><pages>70-76</pages><issn>0305-4179</issn><eissn>1879-1409</eissn><abstract>•The use of bioimpedance spectroscopy (BIS) for monitoring wound healing is explored.•BIS resistance measures can be used to monitor burn wound healing.•BIS phase angle should have further investigation in the assessment of acute burn wound healing.
Assessment of minor burn wound closure is predominately determined by visual inspection and clinical specialist assessment, which remains largely a subjective analysis and results may vary depending on the clinician’s experience. Bioimpedance spectroscopy (BIS) is an instrument that has a demonstrated ability to objectively monitor the wound healing process in various patient populations but has not yet been used in acute burn wounds.
The aim of the pilot study was to examine whether the BIS technique is a valid measure of wound healing.
Localised BIS resistance and phase angle triplicate measures, of minor limb burns, were collected on two serial occasions. Circumference limb measures were taken at the localised burn site to determine a truncated limb volume. Proportional-odds ordered logistic regression analyses determined resistance at zero frequency (R0, indicative of edema) and resistance of total body fluid (Rinf) were significantly associated with healing after adjustment for the influence of surgery. A one unit increase in R0 and Rinf increased the odds of wound healing by 6% and 5% respectively (p<0.01). Phase angle at 50kHz and Ri were not significantly associated with the markers of the wound healing process. Spearman’s correlation determined there was a significant association between a healing wound and limb segment volume (ml) (rho −0.30, p<0.01). BIS is a technique, which has the potential to monitor the progress of wound healing.</abstract><cop>Netherlands</cop><pub>Elsevier Ltd</pub><pmid>28784342</pmid><doi>10.1016/j.burns.2017.06.007</doi><tpages>7</tpages><orcidid>https://orcid.org/0000-0002-7559-6051</orcidid></addata></record> |
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subjects | Adult Bioelectrical impedance Bioimpedance spectroscopy Burns - diagnosis Burns - pathology Dielectric Spectroscopy Female Humans Logistic Models Male Phase angle Pilot Projects Resistance Spectrum Analysis Wound assessment Wound Healing Young Adult |
title | Monitoring wound healing in minor burns—A novel approach |
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