Safety and Trough Concentrations of Nevirapine Prophylaxis Given Daily, Twice Weekly, or Weekly in Breast-Feeding Infants From Birth to 6 Months

Despite the success of antiretroviral prophylaxis in reducing mother-to-child HIV-1 transmission, postpartum transmission through breast milk remains a problem. Antiretroviral administration to the infant during the period of breast-feeding could protect against postnatal transmission. An open-label...

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Veröffentlicht in:	Journal of acquired immune deficiency syndromes (1999) 2003-12, Vol.34 (5), p.482-490
Hauptverfasser:	Shetty, Avinash K, Coovadia, Hoosen M, Mirochnick, Mark M, Maldonado, Yvonne, Mofenson, Lynne M, Eshleman, Susan H, Fleming, Thomas, Emel, Lynda, George, Kathy, Katzenstein, David A, Wells, Jennifer, Maponga, Charles C, Mwatha, Anthony, Jones, Samuel Adeniyi, Abdool Karim, Salim S, Bassett, Mary T
Format:	Artikel
Sprache:	eng
Schlagworte:	Acquired Immunodeficiency Syndrome - prevention & control Acquired Immunodeficiency Syndrome - transmission Adolescent Adult Anti-HIV Agents - administration & dosage Anti-HIV Agents - pharmacokinetics Anti-HIV Agents - therapeutic use Babies Biological and medical sciences Breast Feeding Breastfeeding & lactation Clinical trials Disease transmission Epidemiologic Research Design Female Fundamental and applied biological sciences. Psychology HIV Human immunodeficiency virus Human immunodeficiency virus 1 Human viral diseases Humans Infant Infant, Newborn Infectious diseases Maternal Age Medical sciences Medical treatment Metabolic Clearance Rate Microbiology Miscellaneous Nevirapine - administration & dosage Nevirapine - pharmacokinetics Nevirapine - therapeutic use Pregnancy Pregnancy Complications, Infectious - prevention & control Pregnancy Complications, Infectious - virology Safety South Africa Time Factors Viral diseases Virology Zimbabwe
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