Interaction of levofloxacin with lung surfactant at the air-water interface

[Display omitted] •Levofloxacin expands and stabilizes the lung surfactant film.•Curosurf shows no changes in elasticity after incorporation of levofloxacin.•Levofloxacin is located in the head group region.•Levofloxacin induces an increased Curosurf film organization.•The lung surfactant may be use...

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Veröffentlicht in:	Colloids and surfaces, B, Biointerfaces B, Biointerfaces, 2017-10, Vol.158, p.689-696
Hauptverfasser:	Ortiz-Collazos, Stephanie, Estrada-López, Evelina D., Pedreira, Alline A., Picciani, Paulo H.S., Oliveira, Osvaldo N., Pimentel, Andre S.
Format:	Artikel
Sprache:	eng
Schlagworte:	1,2-Dipalmitoylphosphatidylcholine - chemistry Antibiotic Fluoroquinolone Langmuir film Levofloxacin - chemistry Molecular Dynamics Simulation Pneumonia Pulmonary Surfactants - chemistry Pulmonary system Respiratory distress syndrome Spectrophotometry, Infrared Surface Properties Surface-Active Agents - chemistry Water - chemistry
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