Treatment with tucumã oil (Astrocaryum vulgare) for diabetic mice prevents changes in seric enzymes of the purinergic system: Improvement of immune system

The aim of this study was to evaluate the enzymatic activity of the purinergic system in sera samples from alloxan-induced diabetic mice treated with tucumã oil (Astrocaryum vulgare). For this, the mice were divided into four groups (n=6): control/water (the group CW); control/tucumã oil (the group...

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Veröffentlicht in:Biomedicine & pharmacotherapy 2017-10, Vol.94, p.374-379
Hauptverfasser: Baldissera, Matheus D., Souza, Carine F., Doleski, Pedro H., Grando, Thirssa H., Sagrillo, Michele R., da Silva, Aleksandro S., Leal, Daniela B.R., Monteiro, Silvia G.
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Sprache:eng
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Zusammenfassung:The aim of this study was to evaluate the enzymatic activity of the purinergic system in sera samples from alloxan-induced diabetic mice treated with tucumã oil (Astrocaryum vulgare). For this, the mice were divided into four groups (n=6): control/water (the group CW); control/tucumã oil (the group CT); diabetic/water (the group DW), and diabetic/tucumã oil (the group DT) treated for 14days with 5.0mLkg−1 via oral gavage. On day 14 post-treatment, mice were submitted to euthanasia and blood samples were collected by cardiac puncture. Tucumã oil treatment significantly decreased (p
ISSN:0753-3322
1950-6007
DOI:10.1016/j.biopha.2017.07.113