Glutamate-183 in the conserved TGES motif of domain A of sarcoplasmic reticulum Ca super(2+)-ATPase assists in catalysis of E sub(2)/E sub(2)P partial reactions

The recently determined crystal structures of the sarcoplasmic reticulum Ca super(2+)-ATPase show that in the E sub(1)Ca sub(2) form, domain A is almost isolated from the other cytoplasmic domains, P and N, whereas in E sub(2), domain A has approached domains P and N, with E183 of the highly conserv...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2004-03, Vol.101 (9), p.2776-2781
Hauptverfasser:	Clausen, J D, Vilsen, B, McIntosh, D B, Einholm, A P, Andersen, J P
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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