Two-dimensional salt and temperature DNA denaturation analysis using a magnetoresistive sensor

We present a microfluidic system and its use to measure DNA denaturation curves by varying the temperature or salt (Na ) concentration. The readout is based on real-time measurements of DNA hybridization using magnetoresistive sensors and magnetic nanoparticles (MNPs) as labels. We report the first...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Lab on a chip 2017-07, Vol.17 (13), p.2256-2263
Hauptverfasser:	Rizzi, Giovanni, Dufva, Martin, Hansen, Mikkel Fougt
Format:	Artikel
Sprache:	eng
Schlagworte:	Concentration (composition) Denaturation Deoxyribonucleic acid Magnetoresistivity Melting Microfluidics Platforms Sensors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!