Cross-fostering inhalation toxicity study with HCFC-123 in lactating Sprague-Dawley rats

A study was performed in Sprague-Dawley rats (Crl:CD BR) to differentiate between effects of hydrofluorocarbon 123 (HCFC-123) on the lactating dam or on the fetus using fostering and cross-fostering of the offspring. Pregnant and/or lactating dams without the pups present were exposed to the test su...

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Veröffentlicht in:	Inhalation toxicology 2001-08, Vol.13 (8), p.671-687
Hauptverfasser:	Buschmann, J, Bartsch, W, Dasenbrock, C, Fuhst, R, Pohlmann, G, Preiss, A, Berger-Preiss, E
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Inhalation Animals Body Weight - drug effects Chlorofluorocarbons - pharmacokinetics Chlorofluorocarbons - toxicity Chlorofluorocarbons, Ethane Chromatography, Gas Eating - drug effects Female Homeostasis - drug effects hydrofluorocarbon 123 Lactation - drug effects Magnetic Resonance Spectroscopy Male Milk - chemistry Nutritional Status Nutritive Value Organ Size - drug effects Rats Rats, Sprague-Dawley Survival Analysis
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