Pesticide mixtures potentiate the toxicity in murine thymocytes

The immunotoxic risks of multiple pesticide exposure were evaluated. C57BL/6 mouse thymocytes were exposed to lindane, malathion, and permethrin, either separately or in mixtures of two pesticides, in vitro. These pesticide exposures caused both apoptotic and necrotic cell death in thymocytes as eva...

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Veröffentlicht in:	Toxicology (Amsterdam) 2004-03, Vol.196 (3), p.181-195
Hauptverfasser:	Olgun, Selen, Gogal, Robert M, Adeshina, Femi, Choudhury, Harlal, Misra, Hara P
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Annexin A5 Apoptosis Biological and medical sciences Cells, Cultured Chemical mixtures Coloring Agents Dactinomycin - analogs & derivatives DNA - drug effects Drug Combinations Flow Cytometry Fluorescein-5-isothiocyanate Fluorescent Dyes Immunotoxicity Insecticides - toxicity L-Lactate Dehydrogenase - metabolism Lindane Lindane - toxicity Malathion Malathion - toxicity Male Medical sciences Mice Mice, Inbred C57BL Permethrin Pesticides - toxicity Pesticides, fertilizers and other agrochemicals toxicology Phenotype Propidium Pyrethrins - toxicity T-Lymphocytes - drug effects T-Lymphocytes - enzymology Toxicology
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