Subcellular localization prediction of apoptosis proteins based on evolutionary information and support vector machine

Highlights • The novel evolutionary-conservative information is introduced to represent protein sequences. • Position-specific scoring matrix is divided into several blocks based on the proportion of golden section. • Our method provides the state-of-the-art performance for predicting subcellular lo...

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Veröffentlicht in:	Artificial intelligence in medicine 2017-05, Vol.78, p.41-46
Hauptverfasser:	Xiang, Qilin, Liao, Bo, Li, Xianhong, Xu, Huimin, Chen, Jing, Shi, Zhuoxing, Dai, Qi, Yao, Yuhua
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Apoptosis Apoptosis protein Apoptosis Regulatory Proteins Computational Biology Databases, Protein Evolution, Molecular Golden section Internal Medicine Other Position-specific scoring matrix Proteins Support Vector Machine
Online-Zugang:	Volltext
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