TILLING — a high-throughput harvest for functional genomics

The availability of the whole genome sequence of many model organisms, combined with well-established chemical mutagenesis methods and cost-effective high-throughput DNA genotyping, allows mutations to be identified for virtually any gene. Recently dubbed TILLING (for targeting induced local lesions...

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Veröffentlicht in:	Nature reviews. Genetics 2004-02, Vol.5 (2), p.145-150
1. Verfasser:	Stemple, Derek L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Agriculture Amino Acid Sequence Animal Genetics and Genomics Animals Biological and medical sciences Biomedical and Life Sciences Biomedicine Cancer Research Diverse techniques DNA Mutational Analysis - methods Fundamental and applied biological sciences. Psychology Gene Function Genome, Plant Human Genetics Humans innovation Molecular and cellular biology Molecular Sequence Data Mutagenesis, Site-Directed
Online-Zugang:	Volltext
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