Expression of chondroitin-4-O-sulfotransferase in Escherichia coli and Pichia pastoris

Chondroitin sulfates are linear sulfated polysaccharides called glycosaminoglycans. They are important nutraceutical and pharmaceutical products that are biosynthesized through the action of chondroitin sulfotransferases on either an unsulfated chondroitin or a dermatan polysaccharide precursor. Whi...

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Veröffentlicht in:	Applied microbiology and biotechnology 2017-09, Vol.101 (18), p.6919-6928
Hauptverfasser:	He, Wenqin, Zhu, Yuanyuan, Shirke, Abhijeet, Sun, Xiaojun, Liu, Jian, Gross, Richard A., Koffas, Mattheos A. G., Linhardt, Robert J., Li, Ming
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomedical and Life Sciences Biosynthesis Biotechnologically Relevant Enzymes and Proteins Biotechnology Chondroitin sulfate Cloning E coli Enzymes Escherichia coli Functional foods & nutraceuticals Gene expression Genetic aspects Glycosaminoglycans Glycosylation Golgi apparatus Life Sciences Microbial Genetics and Genomics Microbiology Observations Pichia pastoris Polysaccharides Saccharides Sulfates Sulfotransferase Yeast Yeasts (Fungi)
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