Adherence to Antipsychotic Therapy: Association With Hospitalization and Medicare Spending Among Part D Enrollees With Schizophrenia
Objective:This study examined relationships among antipsychotic adherence, hospitalization, and hospital expenditures in a sample of 13,861 Medicare Part D enrollees with schizophrenia.Methods:Utilization and expenditure data were obtained from the Centers for Medicare and Medicaid Services Chronic...
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| Veröffentlicht in: | Psychiatric services (Washington, D.C.) D.C.), 2017-11, Vol.68 (11), p.1185-1188 |
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| container_title | Psychiatric services (Washington, D.C.) |
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| creator | Roberto, Pamela Brandt, Nicole Onukwugha, Eberechukwu Perfetto, Eleanor Powers, Christopher Stuart, Bruce |
| description | Objective:This study examined relationships among antipsychotic adherence, hospitalization, and hospital expenditures in a sample of 13,861 Medicare Part D enrollees with schizophrenia.Methods:Utilization and expenditure data were obtained from the Centers for Medicare and Medicaid Services Chronic Conditions Warehouse for 2011 and 2012. Adherence was measured with the proportion of days covered and stratified into four categories. Probit regressions and two-part generalized linear models were used to examine relationships between adherence in year 1 and outcomes in year 2.Results:Adherence to antipsychotic therapy was associated with a significantly lower probability of psychiatric hospitalization and significantly lower psychiatric hospital expenditures, with the largest effect sizes observed for the most highly adherent beneficiaries. There was no relationship between antipsychotic adherence and hospitalizations or expenditures for nonpsychiatric conditions.Conclusions:Adherence to antipsychotics among Medicare Part D enrollees with schizophrenia was associated with significantly lower probability of psychiatric hospitalization and lower hospital expenditures. |
| doi_str_mv | 10.1176/appi.ps.201600434 |
| format | Article |
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Adherence was measured with the proportion of days covered and stratified into four categories. Probit regressions and two-part generalized linear models were used to examine relationships between adherence in year 1 and outcomes in year 2.Results:Adherence to antipsychotic therapy was associated with a significantly lower probability of psychiatric hospitalization and significantly lower psychiatric hospital expenditures, with the largest effect sizes observed for the most highly adherent beneficiaries. There was no relationship between antipsychotic adherence and hospitalizations or expenditures for nonpsychiatric conditions.Conclusions:Adherence to antipsychotics among Medicare Part D enrollees with schizophrenia was associated with significantly lower probability of psychiatric hospitalization and lower hospital expenditures.</description><identifier>ISSN: 1075-2730</identifier><identifier>EISSN: 1557-9700</identifier><identifier>DOI: 10.1176/appi.ps.201600434</identifier><identifier>PMID: 28760097</identifier><language>eng</language><publisher>United States: American Psychiatric Association</publisher><subject>Adult ; Antipsychotic Agents - administration & dosage ; Antipsychotics ; Health Expenditures - statistics & numerical data ; Hospitalization ; Hospitalization - statistics & numerical data ; Humans ; Medicare ; Medicare Part D - statistics & numerical data ; Medication Adherence - statistics & numerical data ; Mental health care ; Patient compliance ; Psychotropic drugs ; Schizophrenia ; Schizophrenia - drug therapy ; United States</subject><ispartof>Psychiatric services (Washington, D.C.), 2017-11, Vol.68 (11), p.1185-1188</ispartof><rights>Copyright © 2017 by the American Psychiatric Association 2017</rights><rights>Copyright American Psychiatric Publishing, Inc. Nov 1, 2017</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-a411t-339a4728cb3831b2e22427e4600187c8558496dd7a45039cd5976e85f7d98a4c3</citedby><cites>FETCH-LOGICAL-a411t-339a4728cb3831b2e22427e4600187c8558496dd7a45039cd5976e85f7d98a4c3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://psychiatryonline.org/doi/epdf/10.1176/appi.ps.201600434$$EPDF$$P50$$Gappi$$H</linktopdf><linktohtml>$$Uhttps://psychiatryonline.org/doi/full/10.1176/appi.ps.201600434$$EHTML$$P50$$Gappi$$H</linktohtml><link.rule.ids>314,776,780,2842,21605,21606,21607,27901,27902,77536,77541</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28760097$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Roberto, Pamela</creatorcontrib><creatorcontrib>Brandt, Nicole</creatorcontrib><creatorcontrib>Onukwugha, Eberechukwu</creatorcontrib><creatorcontrib>Perfetto, Eleanor</creatorcontrib><creatorcontrib>Powers, Christopher</creatorcontrib><creatorcontrib>Stuart, Bruce</creatorcontrib><title>Adherence to Antipsychotic Therapy: Association With Hospitalization and Medicare Spending Among Part D Enrollees With Schizophrenia</title><title>Psychiatric services (Washington, D.C.)</title><addtitle>Psychiatr Serv</addtitle><description>Objective:This study examined relationships among antipsychotic adherence, hospitalization, and hospital expenditures in a sample of 13,861 Medicare Part D enrollees with schizophrenia.Methods:Utilization and expenditure data were obtained from the Centers for Medicare and Medicaid Services Chronic Conditions Warehouse for 2011 and 2012. Adherence was measured with the proportion of days covered and stratified into four categories. Probit regressions and two-part generalized linear models were used to examine relationships between adherence in year 1 and outcomes in year 2.Results:Adherence to antipsychotic therapy was associated with a significantly lower probability of psychiatric hospitalization and significantly lower psychiatric hospital expenditures, with the largest effect sizes observed for the most highly adherent beneficiaries. There was no relationship between antipsychotic adherence and hospitalizations or expenditures for nonpsychiatric conditions.Conclusions:Adherence to antipsychotics among Medicare Part D enrollees with schizophrenia was associated with significantly lower probability of psychiatric hospitalization and lower hospital expenditures.</description><subject>Adult</subject><subject>Antipsychotic Agents - administration & dosage</subject><subject>Antipsychotics</subject><subject>Health Expenditures - statistics & numerical data</subject><subject>Hospitalization</subject><subject>Hospitalization - statistics & numerical data</subject><subject>Humans</subject><subject>Medicare</subject><subject>Medicare Part D - statistics & numerical data</subject><subject>Medication Adherence - statistics & numerical data</subject><subject>Mental health care</subject><subject>Patient compliance</subject><subject>Psychotropic drugs</subject><subject>Schizophrenia</subject><subject>Schizophrenia - drug therapy</subject><subject>United States</subject><issn>1075-2730</issn><issn>1557-9700</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kU9vFSEUxYnR2Fr9AG4MiRs388rfAdxN2mpNatqkNS4nPOA5NPMAgbd4XfvBpU5tExM3QC6_c-69OQC8xWiFseiPdUp-lcqKINwjxCh7Bg4x56JTAqHn7Y0E74ig6AC8KuUWIYQF7l-CAyJFEyhxCH4NdnLZBeNgjXAI1aeyN1Os3sCb9qPT_iMcSonG6-pjgN99neB5LMlXPfu7paiDhV-d9UZnB6-TC9aHH3DYxnZe6VzhKTwLOc6zc2VxuDaTv4tpaq29fg1ebPRc3JuH-wh8-3R2c3LeXVx-_nIyXHSaYVw7SpVmgkizppLiNXGEMCIca6tgKYzkXDLVWys044gqY7kSvZN8I6ySmhl6BD4svinHnztX6rj1xbh51sHFXRmxIpxIjKRo6Pt_0Nu4y6FN1yjJRE97hRqFF8rkWEp2mzFlv9V5P2I03kc03kc0pjI-RtQ07x6cd-uts4-Kv5k0YLUAf7RPbf_r-BuyNZzV</recordid><startdate>20171101</startdate><enddate>20171101</enddate><creator>Roberto, Pamela</creator><creator>Brandt, Nicole</creator><creator>Onukwugha, Eberechukwu</creator><creator>Perfetto, Eleanor</creator><creator>Powers, Christopher</creator><creator>Stuart, Bruce</creator><general>American Psychiatric Association</general><general>American Psychiatric Publishing, Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>K9.</scope><scope>NAPCQ</scope><scope>7X8</scope></search><sort><creationdate>20171101</creationdate><title>Adherence to Antipsychotic Therapy: Association With Hospitalization and Medicare Spending Among Part D Enrollees With Schizophrenia</title><author>Roberto, Pamela ; Brandt, Nicole ; Onukwugha, Eberechukwu ; Perfetto, Eleanor ; Powers, Christopher ; Stuart, Bruce</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-a411t-339a4728cb3831b2e22427e4600187c8558496dd7a45039cd5976e85f7d98a4c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Adult</topic><topic>Antipsychotic Agents - administration & dosage</topic><topic>Antipsychotics</topic><topic>Health Expenditures - statistics & numerical data</topic><topic>Hospitalization</topic><topic>Hospitalization - statistics & numerical data</topic><topic>Humans</topic><topic>Medicare</topic><topic>Medicare Part D - statistics & numerical data</topic><topic>Medication Adherence - statistics & numerical data</topic><topic>Mental health care</topic><topic>Patient compliance</topic><topic>Psychotropic drugs</topic><topic>Schizophrenia</topic><topic>Schizophrenia - drug therapy</topic><topic>United States</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Roberto, Pamela</creatorcontrib><creatorcontrib>Brandt, Nicole</creatorcontrib><creatorcontrib>Onukwugha, Eberechukwu</creatorcontrib><creatorcontrib>Perfetto, Eleanor</creatorcontrib><creatorcontrib>Powers, Christopher</creatorcontrib><creatorcontrib>Stuart, Bruce</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Premium</collection><collection>MEDLINE - Academic</collection><jtitle>Psychiatric services (Washington, D.C.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Roberto, Pamela</au><au>Brandt, Nicole</au><au>Onukwugha, Eberechukwu</au><au>Perfetto, Eleanor</au><au>Powers, Christopher</au><au>Stuart, Bruce</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Adherence to Antipsychotic Therapy: Association With Hospitalization and Medicare Spending Among Part D Enrollees With Schizophrenia</atitle><jtitle>Psychiatric services (Washington, D.C.)</jtitle><addtitle>Psychiatr Serv</addtitle><date>2017-11-01</date><risdate>2017</risdate><volume>68</volume><issue>11</issue><spage>1185</spage><epage>1188</epage><pages>1185-1188</pages><issn>1075-2730</issn><eissn>1557-9700</eissn><abstract>Objective:This study examined relationships among antipsychotic adherence, hospitalization, and hospital expenditures in a sample of 13,861 Medicare Part D enrollees with schizophrenia.Methods:Utilization and expenditure data were obtained from the Centers for Medicare and Medicaid Services Chronic Conditions Warehouse for 2011 and 2012. 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| ispartof | Psychiatric services (Washington, D.C.), 2017-11, Vol.68 (11), p.1185-1188 |
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| source | MEDLINE; American Psychiatric Publishing Journals (1997-Present); EZB-FREE-00999 freely available EZB journals |
| subjects | Adult Antipsychotic Agents - administration & dosage Antipsychotics Health Expenditures - statistics & numerical data Hospitalization Hospitalization - statistics & numerical data Humans Medicare Medicare Part D - statistics & numerical data Medication Adherence - statistics & numerical data Mental health care Patient compliance Psychotropic drugs Schizophrenia Schizophrenia - drug therapy United States |
| title | Adherence to Antipsychotic Therapy: Association With Hospitalization and Medicare Spending Among Part D Enrollees With Schizophrenia |
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